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Table 1 Identification of proteins differentially expressed in non-small cell lung cancer tissue interstitial fluid

From: Proteomic analysis of non-small cell lung cancer tissue interstitial fluids

Numbera

Name

Sequence coverageb(%)

Mascot scorec

Molecular weight

Change(−fold)

48

LINE-1 type transposase domain-containing protein 1 (L1TD1)

38

46

98789

Down/13.7

90

Serotransferrin

49

99

77014

Down/3.9

94

Heat shock protein HSP 90-beta

39

50

83212

Up/3.1

103

Complement C3

33

96

187030

Down/6.1

116

Heat shock cognate 71 kDa protein

50

106

70854

Up/4.7

122

Heat shock 70 kDa protein 1A/1B

51

122

70009

Down/8.1

156

Vinculin

23

39

123722

Down/3.1

168

Fibrinogen gamma chain

54

103

51479

Up/3.9

170

Fibrinogen beta chain

45

81

55892

Up/2.4

193

Tubulin-specific chaperone E

34

48

59309

Down/7.7

204

GAS2-like protein 1

37

45

72672

Down/5.7

227

Alpha-enolase

50

68

47139

Up/4.3

230

Zinc finger protein 879

42

49

64536

Up/2.7

272

Putative uncharacterized protein FLJ46541

56

49

18178

Down/2.3

349

Zinc finger protein 658B

52

50

94270

Down/3.4

364

ADP-ribosylation factor-related protein 1

71

44

22599

Up/3.5

386

Zinc finger and SCAN domain-containing protein 10

48

42

80336

Down/2.1

390

Serine/threonine-protein kinase ATR

21

49

301172

Down/2.6

403

Glutathione S-transferase P

56

47

23341

Up/3.0

409

Peroxiredoxin-1

37

54

22096

Up/15.0

434

CAP-Gly domain-containing linker protein 3

34

45

59522

Down/7.0

448

Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

28

41

41874

Up/6.1

459

t-SNARE domain-containing protein 1

23

34

55914

Up/4.8

473

Hemoglobin subunit alpha

68

56

15248

Down/4.4

  1. a Protein spot numbers are highlighted in Figure 1.
  2. b Sequence coverage of the matched peptides in protein by NCBInr Database.
  3. c MASCOT score is a parameter that correlates with the quality of the search result on the MASCOT and SWISS-PROT. High scores are indicative of successful, valid identifications.