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Table 2 Summary of key data from eight reported cases of urachal adenocarcinoma metastatic to the ovaries

From: Surgical and chemotherapeutic experience regarding a urachal carcinoma with repeated relapse: case report and literature review

Reference

Metastasis site

Age

Serum tumor marker

Status with primary urachal carcinoma

Pathology

Immunohistochemistry (positive or negative)

Treatment

Follow-up result

[15]

Right ovary

50

CEA 27.9 ng/m

Simultaneous finding

Not available

-

Surgery

Not available

[16]

Both ovaries, bone, lymph nodes

50

CEA 27.9 ng/ml

Simultaneous finding

High-grade mucinous adenocarcinoma

Cytokeratin 20 and CEA, cytokeratin 7

Surgery and irradiation

Alive with disease (6 months)

[17]

Right ovary, peritoneum, sigmoid colon

54

-

Simultaneous finding

Moderately differentiated mucinous adenocarcinoma

–

Surgery and chemotherapy

Alive with disease (55 months)

[18]

Both ovaries, abdominal wall, colon mass, uterosacral ligament, bladder

64

Normal

Secondary metastasis

Borderline malignant mucinous adenocarcinoma

–

Surgery and chemotherapy

Alive with disease (3 months)

[19]

Both ovaries, bladder

39

Normal

Secondary metastasis

Well-differentiated mucinous adenocarcinoma

–

Surgery and chemotherapy

Died of disease (38 months)

[20]

Both ovaries, peritoneum, bone

26

-

Secondary metastasis

-

–

Surgery and chemotherapy

Died of disease (26 months)

[21]

Left ovary, right lung

30

-

Secondary metastasis

Well-differentiated mucinous adenocarcinoma

–

Surgery and chemotherapy

Alive without disease (11 years)

[22]

Both ovaries

72

-

Pre-finding

Moderately differentiated mucinous adenocarcinoma

–

Surgery and chemotherapy

Alive with disease (36 months)