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Table 1 Reasons for delay or discontinuationin patients who received gemcitabine systemic chemotherapy

From: Severe eosinophilic pneumonia presenting during gemcitabine adjuvant chemotherapy

 

No. of patients (%)

 

Non-hematological, n (%)

Treatment delay, n = 94a

Discontinuation of gemcitabine, n = 6

  Vomiting

5 (5.3)

0

  Infection

10 (10.6)

0

  Drug-induced pneumonia

0

2 (33.3)

  Diarrhea

2 (2.1)

0

  Malaise

4 (4.3)

1 (16.7)

  Patient’s wish

3 (3.2)

0

Hematological, n (%)

  

  Neutrophil count decreased

36 (38.3)

0

  Anemia

7 (7.4)

1 (16.7)

  Platelet count decreased

15 (16.0)

1 (16.7)

  AST or ALT increased

4 (4.3)

0

  Blood bilirubin increased

5 (5.3)

1 (16.7)

  Creatinine increased

1 (1.1)

0

  Hypoalbuminemia

2 (2.1)

0

  1. Abbreviations: ALT, Alanine aminotransferase; AST, Aspartate aminotransferase.
  2. aTotal exceeds 92 because of the duplication of patients.