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Table 2 Univariate Cox regression analysis of disease-specific survival a

From: Prognostic analysis of esophageal cancer in elderly patients: metastatic lymph node ratio versus 2010 AJCC classification by lymph nodes

Characteristics

Cases (n, %)

DSS (%)

HR (95% CI)

P value

Age (yr)

   

0.838

  ≤75

97 (73.5)

46.4

1.000

 

  >75

35 (26.5)

42.9

1.055 (0.629 to 1.770)

 

Gender

    

  Female

11 (8.3)

54.5

1.000

0.474

  Male

121 (91.7)

44.6

1.394 (0.561 to 3.460)

 

Tumor size (cm)

   

0.081

  ≤5

91 (68.9)

52.7

1.000

 

  >5

41 (31.1)

29.3

1.524 (0.950 to 2.443)

 

Tumor location

   

0.778

  Upper

6 (4.5)

50.0

1.000

 

  Middle

55 (41.7)

45.5

0.938 (0.286 to 3.081)

0.916

  Lower

71 (53.8)

45.1

1.114 (0.344 to 3.613)

0.857

Histologic grade

   

0.073

  Well

17 (12.9)

58.8

1.000

 

  Moderately

81 (61.4)

48.1

1.587 (0.712 to 3.538)

0.259

  Poorly

34 (25.7)

32.4

2.461 (1.053 to 5.752)

0.038

Vessel involvement

   

0.029

  No

100 (75.8)

48.0

1.000

 

  Yes

32 (24.2)

37.5

1.786 (1.061 to 3.007)

 

Perineural invasion

   

0.007

  No

113 (85.6)

49.6

1.000

 

  Yes

19 (14.4)

21.1

2.198 (1.240 to 3.894)

 

Tumor grade

   

0.003

  T1

19 (14.4)

89.5

  

  T2

16 (12.1)

68.8

4.319 (0.854 to 12.727)

0.069

  T3

89 (67.4)

33.7

7.731 (2.868 to 14.844)

0.003

  T4

8 (6.1)

25.0

10.551 (2.969 to 21.902)

0.001

TLN (nodes)

   

0.729

  ≤18

47 (35.6)

44.7

1.000

 

  >18

85 (64.4)

45.9

0.905 (0.597 to 1.427)

 

N stage

   

<0.001

  N0

58 (43.9)

65.5

1.000

 

  N1

42 (31.8)

42.9

2.059 (1.136 to 3.732)

0.017

  N2

18 (13.7)

22.2

4.122 (2.047 to 8.299)

<0.001

  N3

14 (10.6)

0

19.108 (8.503 to 42.939)

<0.001

MLNR stage

   

<0.001

  MLNR0

58 (43.9)

65.5

  

  MLNR1

40 (30.3)

45.0

1.963 (1.070 to 3.602)

0.026

  MLNR2

19 (14.4)

21.1

4.142 (2.902 to 8.202)

<0.001

  MLNR3

15 (11.4)

0

12.037 (5.866 to 24.698)

<0.001

  1. aCI, confidence interval; DSS, disease-specific survival; HR, hazard ratio.