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Table 2 Cox regression survival analysis of factors predicting survival time of patients with gastric cancer

From: Double-positive expression of high-mobility group box 1 and vascular endothelial growth factor C indicates a poorer prognosis in gastric cancer patients

Clinicopathological characteristics

Hazard ratio

95.0% CI for Exp (B)

P value

   

Lower

Upper

Borrmann:

    

I and II

1

   

III and IV

0.78

0.21

2.85

0.7072

Histologic differentiation:

    

Well and moderate

1

   

Poorly

1.26

0.67

2.38

0.4756

Tumor size:

    

<4 cm

1

   

≥4 cm

1.17

0.63

2.18

0.6277

pT stage:

    

pT1 and pT2

1

   

pT3 and pT4

1.99

0.60

6.60

0.2595

Lymph node metastasis:

    

Absence

1

   

Presence

2.58

1.01

5.06

0.0480

TNM stage:

    

I, II

1

   

III, IV

2.70

1.06

7.03

0.0296

High-mobility group box 1 (HMGB1)expression:

    

Negative

1

   

Positive

2.66

1.04

6.32

0.0370

Vascular endothelial growth factor C (VEGF-C) expression:

    

Negative

1

   

Positive

2.62

1.03

6.83

0.0464

HMGB1 and VEGF-C

    

Othersa

1

   

Combined HMGB1and VEGF-C expression

    
 

2.78

1.21

6.40

0.0162

  1. aOthers were HMGB1 negative and VEGF-C negative, HMGB1 negative and VEGF-C positive, and HMGB1 positive and VEGF-C negative.
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World Journal of Surgical Oncology

ISSN: 1477-7819

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