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Figure 1 | World Journal of Surgical Oncology

Figure 1

From: Double-positive expression of high-mobility group box 1 and vascular endothelial growth factor C indicates a poorer prognosis in gastric cancer patients

Figure 1

Immunohistochemical labeling of vascular endothelial growth factor C (VEGF-C) and high-mobility group box 1 (HMGB1) in primary gastric cancer (GC) and normal gastric tissue. Tissue microarrays of GC and non-gastric carcinoma tissue are shown (A,B). HMGB1 was significantly increased in GC tissues. HMGB1 was mainly localized to the nucleus but,when compared to the normal gastric tissue (C), was effusive to the cytoplasm and stroma in some cases (D). The cytoplasmic expression of VEGF-C,when compared to the negative corresponding samples (E), yielded similar results (F). Bar, 50 μm.

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