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Table 1 The volume and weight of colon tumor ※

From: Increase of cyclooxygenase-2 inhibition with celecoxib combined with 5-FU enhances tumor cell apoptosis and antitumor efficacy in a subcutaneous implantation tumor model of human colon cancer

Group

Volume of tumor (cm3)

Weight of tumor (g)

control

0.5367 ± 0.0532

0.5924 ± 0.0612

5-FU

0.3429 ± 0.0875a

0.4276 ± 0.0629a

celecoxib

0.1947 ± 0.0386a

0.2783 ± 0.0314a

5-FU + celecoxib

0.1428 ± 0.0236a,b,c

0.1281 ± 0.0219a,b,c

  1. Note: ※ Values represent the mean ± SD; a There were significant differences in the volume and the weight of tumors between each treatment group compared with the control group, P <0.05. b Compared with the 5-FU group, the volume and the weight of tumors were dramatically lower in the 5-FU + celecoxib group, P <0.05. C Compared with the celecoxib group, the volume and the weight of tumors were also significantly lower in the 5-FU + celecoxib group, P <0.05.