Figure 4From: Increase of cyclooxygenase-2 inhibition with celecoxib combined with 5-FU enhances tumor cell apoptosis and antitumor efficacy in a subcutaneous implantation tumor model of human colon cancerDetection of apoptotic tumor cells by TUNEL assay. TUNEL-positive cells (apoptotic cells) were stained black-brown (magnification: × 400). There were more apoptotic cells in the 5-FU + celecoxib group than in the other groups. (A, control group; B, 5-FU group; C, celecoxib group; D, 5-FU + celecoxib group).Back to article page