Study
|
Study design
|
Data analysis
|
Allocation generation
|
Allocation concealment
|
Blinding
|
Lost to follow-up
|
---|
Andersen, 2000
|
RCT
|
ITT
|
Unclear
|
Unclear
|
None reported
|
9.5% at 12 months
|
Devoogdt, 2011
|
RCT
|
ITT
|
Adequate
|
Adequate
|
Assessor blinded
|
4% at 12 months
|
Didem, 2005
|
RCT
|
PP
|
Sealed envelopes
|
Adequate
|
Patient blinded
|
5.4% at 1 months
|
Johansson, 1998
|
RCT
|
PP
|
Unclear
|
Unclear
|
None reported
|
None
|
Johansson, 1999
|
RCT
|
PP
|
Inadequate
|
Unclear
|
None reported
|
None
|
McNeely, 2004
|
RCT
|
PP
|
Computer-generated
|
Adequate
|
Assessor blinded
|
11.1% at 1 months
|
Williams, 2002
|
RCT crossover
|
PP
|
Unclear
|
Unclear
|
None reported
|
None
|
Sitzia, 2002
|
RCT
|
PP
|
Computer-generated
|
Adequate
|
None reported
|
3.6% at 2 weeks
|
Szolnoky, 2009
|
RCT
|
ITT
|
Unclear
|
Unclear
|
None reported
|
None
|
Torres Lacomba, 2010
|
RCT
|
PP
|
Computer-generated
|
Unclear
|
Assessor blinded
|
3.3% at 12 months
|
- Abbreviations: PP, per-protocol; RCT, randomized controlled trial; ITT, intention-to-treat.