Clinicopathological features and CCT2 and PDIA2 expression in gallbladder squamous/adenosquamous carcinoma and gallbladder adenocarcinoma

Table 2 The relationship between CCT2 and PDIA3 expression and clinicopathological features of gallbladder SC/ASC

Clinicalpathological features	Case number	CCT2			PDIA3
Clinicalpathological features	Case number	Positive number (%)	χ²	P	Positive number (%)	χ²	P
Gender
male	19	7(36.8)	2.242	0.134	12(63.2)	0.580	0.446
female	27	16(59.3)	2.242	0.134	14(51.9)	0.580	0.446
Age (years)
≤ 45	3	1(33.3)	0.357	0.550	1(33.3)	0.702	0.402
> 45	43	22(51.2)	0.357	0.550	25(58.1)	0.702	0.402
Pathological types
SC	26	14(53.8)	0.354	0.552	18(69.2)	3.930	0.047
ASC	20	9(45.0)			8(40.0)
Degree of differentiation^a
well-differentiated	16	8(50.0)	3.333	0.189	8(50.0)	5.940	0.051
moderately-differentiated	24	10(41.7)			12(50.0)
poorly-differentiated	6	5(83.3)			6(100.0)
Tumor maximum diameter (cm)
≤ 3 cm	20	6(30.0)	5.121	0.020	9(45.0)	1.911	0.167
> 3 cm	26	17(65.4)	5.121	0.020	17(65.4)	1.911	0.167
Gallbladder stones
no	18	10(55.6)	0.365	0.546	12(66.7)	0.351	0.554
yes	28	13(46.4)			14(50.0)
TNM stage
I + II	12	3(25.0)			5(41.7)
III	20	8(40.0)	10.943	0.005	9(45.0)	7.013	0.028
IV	14	12(85.7)			12(85.7)
Lymph node metastasis
no	17	5(29.4)	4.572	0.033	6(35.5)	4.945	0.026
yes	29	18(62.1)	4.572	0.033	20(69.0)	4.945	0.026
Invasion
no	16	5(31.3)	3.450	0.063	5(31.3)	6.376	0.012
yes	30	18(60.0)	3.450	0.063	21(70.0)	6.376	0.012
Surgical
radical	14	4(28.6)	5.143	0.076	6(42.8)	6.987	0.030
palliative	18	9(50.0)	5.143	0.076	8(44.4)	6.987	0.030
biopsy	14	10(71.4)			12(85.7)

^aComparison between well-differentiated and moderately-differentiated SC/ ASC: P_CCT2 = 0.333; P_PDIA3 = 0.051; Comparison between moderately-differentiated and poorly-differentiated SC/ ASC: P_CCT2 = 0.169; P_PDIA3 = 0.057.

ISSN: 1477-7819