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Table 2 The relationship between CCT2 and PDIA3 expression and clinicopathological features of gallbladder SC/ASC

From: Clinicopathological features and CCT2 and PDIA2 expression in gallbladder squamous/adenosquamous carcinoma and gallbladder adenocarcinoma

Clinicalpathological features Case number CCT2 PDIA3
Positive number (%) χ2 P Positive number (%) χ2 P
Gender        
male 19 7(36.8) 2.242 0.134 12(63.2) 0.580 0.446
female 27 16(59.3) 14(51.9)
Age (years)        
≤ 45 3 1(33.3) 0.357 0.550 1(33.3) 0.702 0.402
> 45 43 22(51.2) 25(58.1)
Pathological types        
SC 26 14(53.8) 0.354 0.552 18(69.2) 3.930 0.047
ASC 20 9(45.0)    8(40.0)   
Degree of differentiationa        
well-differentiated 16 8(50.0) 3.333 0.189 8(50.0) 5.940 0.051
moderately-differentiated 24 10(41.7) 12(50.0)
poorly-differentiated 6 5(83.3) 6(100.0)
Tumor maximum diameter (cm)        
≤ 3 cm 20 6(30.0) 5.121 0.020 9(45.0) 1.911 0.167
> 3 cm 26 17(65.4) 17(65.4)
Gallbladder stones        
no 18 10(55.6) 0.365 0.546 12(66.7) 0.351 0.554
yes 28 13(46.4)    14(50.0)   
TNM stage        
I + II 12 3(25.0)    5(41.7)   
III 20 8(40.0) 10.943 0.005 9(45.0) 7.013 0.028
IV 14 12(85.7)    12(85.7)   
Lymph node metastasis        
no 17 5(29.4) 4.572 0.033 6(35.5) 4.945 0.026
yes 29 18(62.1) 20(69.0)
Invasion        
no 16 5(31.3) 3.450 0.063 5(31.3) 6.376 0.012
yes 30 18(60.0) 21(70.0)
Surgical        
radical 14 4(28.6) 5.143 0.076 6(42.8) 6.987 0.030
palliative 18 9(50.0) 8(44.4)
biopsy 14 10(71.4)    12(85.7)   
  1. aComparison between well-differentiated and moderately-differentiated SC/ ASC: PCCT2 = 0.333; PPDIA3 = 0.051; Comparison between moderately-differentiated and poorly-differentiated SC/ ASC: PCCT2 = 0.169; PPDIA3 = 0.057.