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Table 4 Factor analysis including both independent and dependent variables studied in relation to colorectal cancer morphology a,b

From: Clinicopathological analysis of colorectal cancer: a comparison between emergency and elective surgical cases

 

Factor (component)c

1

2

3

4

5

6

7

Nature of surgery

0.444

−0.077

−0.135

−0.239

0.418

0.302

−0.348

Gender

0.021

−0.054

0.031

−0.161

0.485

−0.448

0.156

Age group

−0.232

0.006

0.060

0.024

0.098

0.458

0.493

Location

0.014

−0.195

−0.225

−0.119

−0.693d

−0.043

−0.028

>1 tumor

−0.017

0.013

−0.049

−0.172

0.225

0.644d

0.025

Tumor diameter

0.027

0.216

0.320

0.648d

0.150

−0.065

−0.184

AJCC stage

0.758d

0.074

−0.030

0.368

0.008

0.145

−0.055

Tumor (T) stage

0.519

0.157

−0.058

0.559

0.208

−0.030

0.008

Node (N) stage

0.754d

0.080

0.009

0.173

−0.113

0.101

−0.026

Differentiation

−0.236

−0.159

−0.776d

−0.055

−0.025

0.012

0.015

Mucin production

0.001

0.950d

0.023

0.025

0.073

0.027

−0.040

Mucin type

0.083

0.926d

0.092

0.039

0.103

0.018

0.001

Crohn-likee

−0.153

0.048

0.089

0.225

0.657d

0.019

−0.021

TILs

−0.207

0.097

0.611d

−0.031

0.205

0.017

0.085

Desmoplasia

0.206

−0.023

−0.372

0.471d

0.157

−0.044

0.217

Necrosis

0.041

−0.445

−0.008

0.601

−0.021

0.016

0.177

Vascular invasion

0.586d

−0.110

0.114

−0.023

0.038

−0.142

−0.002

Perineural invasion

0.609d

0.015

−0.041

−0.058

−0.090

−0.134

0.168

Medullary type

−0.027

−0.118

0.837 d

0.049

0.093

0.063

0.046

Budding

0.379

−0.122

0.086

0.041

0.040

0.004

0.683d

Tumor margin

0.547d

0.101

−0.255

−0.026

−0.119

−0.069

0.356

Family history

0.006

−0.006

−0.084

−0.038

0.128

−0.522d

−0.025

  1. AJCC American Joint Committee on Cancer, TILs tumor-infiltrating lymphocytes.
  2. aVariables with loading of >0.40 are usually applied as meaningful loadings on the factor. If a variable has a meaningful loading on more than one component, that variable should be ignored in the interpretation.
  3. bA minus (−) before the value indicates a negative correlation.
  4. cFactors: 1, Variables related to aggressiveness and extent of tumor spread; 2, factors related to mucin production/mucin type; 3, factors related to microsatellite instability type of colorectal cancer; 4, factors related to tumor size and desmoplastic response to tumor growth; 5, location and peri-tumor lymphocytic infiltration; 6, family history and multiple tumors; 7, budding.
  5. dThe variable is applied as a meaningful loading on that component.
  6. eCrohn-like lymphocytic reaction.