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Table 4 Factor analysis including both independent and dependent variables studied in relation to colorectal cancer morphology a,b

From: Clinicopathological analysis of colorectal cancer: a comparison between emergency and elective surgical cases

  Factor (component)c
1 2 3 4 5 6 7
Nature of surgery 0.444 −0.077 −0.135 −0.239 0.418 0.302 −0.348
Gender 0.021 −0.054 0.031 −0.161 0.485 −0.448 0.156
Age group −0.232 0.006 0.060 0.024 0.098 0.458 0.493
Location 0.014 −0.195 −0.225 −0.119 −0.693d −0.043 −0.028
>1 tumor −0.017 0.013 −0.049 −0.172 0.225 0.644d 0.025
Tumor diameter 0.027 0.216 0.320 0.648d 0.150 −0.065 −0.184
AJCC stage 0.758d 0.074 −0.030 0.368 0.008 0.145 −0.055
Tumor (T) stage 0.519 0.157 −0.058 0.559 0.208 −0.030 0.008
Node (N) stage 0.754d 0.080 0.009 0.173 −0.113 0.101 −0.026
Differentiation −0.236 −0.159 −0.776d −0.055 −0.025 0.012 0.015
Mucin production 0.001 0.950d 0.023 0.025 0.073 0.027 −0.040
Mucin type 0.083 0.926d 0.092 0.039 0.103 0.018 0.001
Crohn-likee −0.153 0.048 0.089 0.225 0.657d 0.019 −0.021
TILs −0.207 0.097 0.611d −0.031 0.205 0.017 0.085
Desmoplasia 0.206 −0.023 −0.372 0.471d 0.157 −0.044 0.217
Necrosis 0.041 −0.445 −0.008 0.601 −0.021 0.016 0.177
Vascular invasion 0.586d −0.110 0.114 −0.023 0.038 −0.142 −0.002
Perineural invasion 0.609d 0.015 −0.041 −0.058 −0.090 −0.134 0.168
Medullary type −0.027 −0.118 0.837 d 0.049 0.093 0.063 0.046
Budding 0.379 −0.122 0.086 0.041 0.040 0.004 0.683d
Tumor margin 0.547d 0.101 −0.255 −0.026 −0.119 −0.069 0.356
Family history 0.006 −0.006 −0.084 −0.038 0.128 −0.522d −0.025
  1. AJCC American Joint Committee on Cancer, TILs tumor-infiltrating lymphocytes.
  2. aVariables with loading of >0.40 are usually applied as meaningful loadings on the factor. If a variable has a meaningful loading on more than one component, that variable should be ignored in the interpretation.
  3. bA minus (−) before the value indicates a negative correlation.
  4. cFactors: 1, Variables related to aggressiveness and extent of tumor spread; 2, factors related to mucin production/mucin type; 3, factors related to microsatellite instability type of colorectal cancer; 4, factors related to tumor size and desmoplastic response to tumor growth; 5, location and peri-tumor lymphocytic infiltration; 6, family history and multiple tumors; 7, budding.
  5. dThe variable is applied as a meaningful loading on that component.
  6. eCrohn-like lymphocytic reaction.