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Table 3 Multivariate analysis of clinical and pathologic features in relation to nature of surgery, gender, age group, tumor location, and family history a,b

From: Clinicopathological analysis of colorectal cancer: a comparison between emergency and elective surgical cases

 

AJCC stage (II, III, and IV vs. I)

T stage (T2, T3, and T4 vs. T1)

N stage (N1 and N2/N3 vs. N0)

Mucin production (0 to 50% and >50% vs. 0%)

Type of surgery

    

 Elective (n = 845)

RC

RC

RC

RC

 Emergency (n = 129) 

II

2.854

T2

0.838

N1

3.186

0 to 50%

1.052

P = 0.03c

P = 0.81

P<0.0001c

P = 0.83

III

6.932

T3

2.853

N2/N3

2.679

>50%

1.093

P<0.0001c

P = 0.09

P<0.0001c

P = 0.75

 

IV

5.019

T4

4.056

    

P=0.006 c

P=0.03 c

Gender

        

 Male

RC

RC

RC

RC

 Female

II

0.863

T2

1.369

N1

0.761

0-50%

0.986

P = 0.44

P = 0.29

P = 0.11

P = 0.93

III

0.782

T3

1.006

N2/N3

0.916

>50%

0.694

P = 0.20

P = 0.98

 

P = 0.62

P = 0.07

IV

0.844

T4

1.494

P = 0.66

P = 0.21

Age group

        

 >75 years

RC

RC

RC

RC

 60 to 75 years

II

1.538

T2

1.017

N1

0.790

0-50%

0.713

P = 0.04 c

P = 0.96

P = 0.22

P = 0.06

III

1.414

T3

1.361

N2/N3

1.462

>50%

1.229

P = 0.10

P = 0.30

P = 0.07

P = 0.39

IV

1.829

T4

1.842

–

–

–

–

P = 0.13

P = 0.09

–

–

–

–

 <60 years

II

1.830

T2

1.265

N1

1.117

0 to 50%

0.658

P = 0.04c

P = 0.61

P = 0.65

P = 0.09

III

2.019

T3

1.998

N2/N3

1.919

>50%

1.967

P = 0.01c

P = 0.10

P = 0.01c

–

P=0.02 c –

IV

3.203

T4

3.155

–

–

–

–

P = 0.02c

P = 0.02c

–

–

–

–

Localization

        

 Right colon

RC

RC

RC

RC

 Left colon

II

0.513

T2

0.333

N1

1.168

0 to 50%

0.447

P = 0.009c

P = 0.02c

P = 0.469

P<0.0001c

III

0.680

T3

0.232

N2/N3

1.194

>50%

0.364

P = 0.14

P <0.0001c

–

P=0.42

–

P<0.0001 c

IV

0.616

T4

0.297

–

–

–

–

P = 0.22

P = 0.006c

–

–

–

–

 Rectum

II

0.228

T2

0.642

N1

1.347

0 to 50%

0.400

P<0.0001c

P = 0.31

P = 0.16

P<0.0001c

III

0.470

T3

0.196

N2/N3

1.120

>50%

0.269

P = 0.002c

P<0.0001c

P = 0.61

P<0.0001c

IV

0.113

T4

0.119

–

–

–

–

P<0.0001c

P<0.0001c

–

–

–

–

Family history

        

 Sporadic

RC

RC

RC

RC

 Familial

II

1.161

T2

1.462

N1

1.099

N1 ]

1.161

P = 0.54

P = 0.36

P = 0.65

P = 0.44

III

1.308

T3

1.588

N2/N3

0.963

N2/N3

0.670

P = 0.26

P = 0.22

P = 0.76

P = 0.13

IV

0.760

T4

1.419

–

–

–

–

P = 0.56

P = 0.42

–

–

–

–

Nagelkerke R2

–

0.121

–

0.132

–

0.058

–

0.088

  1. AJCC American Joint Committee on Cancer, N node, RC reference category, T tumor.
  2. aAJCC stage I, T1, N0, and 0% mucin are reference groups in analysis of AJCC, T, and N stage, and mucin production, respectively.
  3. bData are presented as odds ratios and P values.
  4. cSignificant.
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World Journal of Surgical Oncology

ISSN: 1477-7819

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