Clinicopathological analysis of colorectal cancer: a comparison between emergency and elective surgical cases

Table 1 Univariate comparison of clinical and pathologic features in cases of colorectal cancer treated surgically on electively and as an emergency

Feature	Elective (n = 845)	Emergency (n = 129)	OR/diff^a	P-value for OR/diff^a
> 1 tumors, %	4.5	11.7	2.816	0.001^b
Mean tumor diameter, mm	47	48	0.97	0.68
AJCC stage, %
I	21.4	3.9	RC
II	39.1	31.2	4.382	0.002^b
III	35.1	57.0	8.900	<0.0001^b
IV	4.3	7.8	9.889	<0.0001^b
T, %
1	7.7	2.3	RC
2	20.0	4.7	0.771	0.72
3	60.5	68.8	3.747	0.03^b
4	11.7	24.2	6.818	0.002 ^b
N, %
0	61.5	36.0	RC
1	19.7	33.6	2.912	<0.0001^b
2 or 3	18.8	30.4	2.757	<0.0001 ^b
Proportion of poorly differentiated tumors, %^c	10.9	14.7	1.412	0.21
Mucin production, %
0%	62.4	56.6	RC
0 to 50%	24.2	25.6	1.168	0.49
>50%, mucinous type	13.4	17.8	1.468	0.14
Mucin type, if mucinous, %
Extracellular	88.3	69.8	RC
Signet-ring-type component	11.7	30.2	3.267	0.001^b
Crohn-like lymphocytic reaction, %	59.8	69.8	1.554	0.03^b
TILs
≤30/10 HPFs	80.7	88.4	RC
>30/10 HPFs	19.3	11.6	0.551	0.04^b
Desmoplasia,^d %	82.6	90.9	2.110	0.03^b
Necrosis,^d %	66.3	61.7	0.816	0.33
Vascular invasion, %	22.2	37.3	2.086	<0.0001^b
Perineural invasion, %	16.4	28.6	2.032	0.001^b
Medullary type, %	4.8	3.2	0.646	0.41
Budding,^d %	40.0	45.5	1.248	0.28
Tumor margin, %
Circumscribed	54.5	41.9	RC
Infiltrative	45.5	58.1	1.666	0.008^b

AJCC American Joint Committee on Cancer, HPF high-power field, N node, RC reference category, T tumor, TILs Tumor-infiltrating lymphocytes.
^aEmergency versus elective. Odds ratio except for tumor diameter where difference (mm) is stated.
^bSignificantly different.
^cIn major tumor component.
^dRectal cancers were omitted from the analysis of necrosis, desmoplasia, and budding because of preoperative radiotherapy.

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