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Table 1 Incidence of 30-day postoperative outcomes in young and older patients undergoing the Whipple procedure

From: Postoperative outcomes following pancreaticoduodenectomy: how should age affect clinical practice?

Outcome

Young

Older

P value

OR (95% CI)a

 

n = 1051

n= 994

  

MORTALITY

20 (1.9)

36 (3.6)

0.017

1.94 (1.11-3.37)

MORBIDITY

    

Wound

154 (14.7)

149 (15.0)

0.830

1.03 (0.81-1.31)

  Deep incisional SSI

27 (2.6)

29 (2.9)

0.629

1.14 (0.67-1.94)

  Organ/space incisional SSI

122 (11.6)

110 (11.1)

0.700

0.95 (0.72-1.25)

  Wound dehiscence

17 (1.6)

24 (2.4)

0.199

1.51 (0.80-2.82)

Respiratory

99 (9.4)

124 (12.5)

0.027

1.37 (1.04-1.81)

  Pneumonia

53 (5.0)

65 (6.5)

0.147

1.32 (0.91-1.91)

  Unplanned intubation

48 (4.6)

69 (6.9)

0.021

1.56 (1.07-2.28)

  Ventilator support >48 h

58 (5.5)

77 (7.7)

0.043

1.44 (1.01-2.05)

Cardiac

13 (1.2)

22 (2.2)

0.089

1.81 (0.91-3.61)

  Myocardial infarction

3 (0.3)

9 (0.9)

0.067

3.19 (0.86-11.82)

  Cardiac arrest necessitating CPR

10 (1.0)

16 (1.6)

0.184

1.70 (0.77-3.77)

Renal

21 (2.0)

25 (2.5)

0.431

1.27 (0.70-2.28)

  Acute renal failure

11 (1.0)

8 (0.8)

0.569

0.77 (0.31-1.92)

  Progressive renal insufficiency

14 (1.3)

17 (1.7)

0.484

1.29 (0.63-2.63)

Venous thromboembolism

30 (2.9)

38 (3.8)

0.222

1.35 (0.83-2.20)

  Deep vein thrombosis

23 (2.2)

23 (2.3)

0.848

1.06 (0.59-1.90)

  Pulmonary embolism

11 (1.0)

15 (1.5)

0.351

1.45 (0.66-3.17)

Systemic sepsis

156 (14.8)

159 (16.0)

0.470

1.09 (0.86-1.39)

  Sepsis

130 (12.4)

102 (10.3)

0.133

0.81 (0.62-1.07)

  Septic shock

33 (3.1)

61 (6.1)

0.001

2.03 (1.31-3.11)

Cerebrovascular accident

2 (0.2)

2 (0.2)

0.955

1.06 (0.15-7.52)

Major bleeding b

19 (1.8)

14 (1.4)

0.474

0.78 (0.39-1.56)

Return to operating room

91 (8.7)

82 (8.2)

0.740

0.95 (0.69-1.30)

  1. Data presented as n (%).
  2. aOdds of outcome in patients >65 years compared with ≤65 years (referent group).
  3. bRequiring >4 units of packed red blood cells within first 72 h postoperatively.
  4. OR odds ratio, CI confidence interval, SSI surgical site infection, CPR cardiopulmonary resuscitation.