Unique clinicopathological features of metaplastic breast carcinoma compared with invasive ductal carcinoma and poor prognostic indicators

Table 3 Multivariate analysis of 5-year overall survival and 5-year disease-free survival in metaplastic breast cancer

		5-year OS			5-year DFS
	HR	95% CI	P	HR	95% CI	P
Pathological tumor stage (>T3)	3.224	1.32 to 7.89	0.010	2.962	1.19 to 7.39	0.020
Pathological nodal stage (positive)	3.170	1.31 to 7.67	0.010	1.594	1.08 to 2.35	0.018
Histological grade (3)	0.945	0.24 to 3.70	0.935	1.066	0.28 to 4.07	0.925
P53 (≥25%)	3.274	0.40 to 26.72	0.268	3.413	0.43 to 27.38	0.248
Ki-67 (≥14%)	2.926	1.08 to 7.96	0.035	2.719	1.00 to 7.41	0.049
Hormone therapy (yes)	0.290	0.06 to 1.42	0.126	0.341	0.07 to 1.68	0.185
Subtypes of MBC (SPC)	1.388	0.54 to 3.59	0.499	—	—	—

MBC, metaplastic breast cancer;SPC, adenocarcinoma with spindle cell differentiation.

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