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Table 3 Multivariate analysis of 5-year overall survival and 5-year disease-free survival in metaplastic breast cancer

From: Unique clinicopathological features of metaplastic breast carcinoma compared with invasive ductal carcinoma and poor prognostic indicators

   5-year OS    5-year DFS  
HR 95% CI P HR 95% CI P
Pathological tumor stage (>T3) 3.224 1.32 to 7.89 0.010 2.962 1.19 to 7.39 0.020
Pathological nodal stage (positive) 3.170 1.31 to 7.67 0.010 1.594 1.08 to 2.35 0.018
Histological grade (3) 0.945 0.24 to 3.70 0.935 1.066 0.28 to 4.07 0.925
P53 (≥25%) 3.274 0.40 to 26.72 0.268 3.413 0.43 to 27.38 0.248
Ki-67 (≥14%) 2.926 1.08 to 7.96 0.035 2.719 1.00 to 7.41 0.049
Hormone therapy (yes) 0.290 0.06 to 1.42 0.126 0.341 0.07 to 1.68 0.185
Subtypes of MBC (SPC) 1.388 0.54 to 3.59 0.499
  1. MBC, metaplastic breast cancer;SPC, adenocarcinoma with spindle cell differentiation.