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Figure 2 | World Journal of Surgical Oncology

Figure 2

From: Hydroxycamptothecin induces apoptosis and inhibits tumor growth in colon cancer by the downregulation of survivin and XIAP expression

Figure 2

HCPT induces apoptosis in colon cancer cells. SW1116 (A) and Colo 205 (B) were treated with 10-hydroxycamptothecin (HCPT) (2.5 μg/mL) at the indicated time. Apoptosis was determined by terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end labeling (TUNEL) staining. The data represent the means ± SD from three independent experiments; *P < 0.01, compared to the PBS group. (C) SW1116 and Colo 205 were treated with HCPT (2.5 μg/mL) at the indicated dose for 48 hours. Apoptosis was determined by TUNEL staining. The data represent the means ± SD from three independent experiments; *P < 0.01, compared to PBS treatment.

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