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Table 2 Clinicopathological characteristics based on hENT1, dCK, and RRM1 expression for advanced biliary tract cancer subjects

From: Prognostic predictive values of gemcitabine sensitivity-related gene products for unresectable or recurrent biliary tract cancer treated with gemcitabine alone

Characteristic

hENT1 expression

P value

dCK expression

P value

RRM1 expression

P value

 

Low ( n = 11)

High ( n = 17)

 

Low ( n = 13)

High ( n = 15)

 

Low ( n = 11)

High ( n = 17)

 

Primary tumor site

         

  Extrahepatic bile duct

7

11

1.000

10

8

0.254

8

10

0.689

  Gallbladder

4

6

 

3

7

 

3

7

 

Recurrence or unresectable

         

  Recurrence after surgery

9

13

1.000

9

13

0.372

7

15

0.174

  Unresectable

2

4

 

4

2

 

4

2

 

Histological type

         

  Well/moderately

9

12

0.668

11

10

0.396

9

12

0.668

  Poor

2

5

 

2

5

 

2

5

 

hENT1 expression

         

  High

–

–

–

7

10

0.700

6

11

0.701

  Low

–

–

 

6

5

 

5

6

 

dCK expression

         

  High

*

*

*

–

–

–

2

13

0.006

  Low

*

*

 

–

–

 

9

4

 
  1. dCK, deoxycytidine kinase; hENT1, human equilibrative nucleoside transporter; RRM1, ribonucleotide reductase subunit M1. *Same as above line (hENT1 expression).