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Table 3 Frequency of curve types

From: Evaluation of chemosensitivity prediction using quantitative dose–response curve classification for highly advanced/relapsed gastric cancer

Curve Typesa

Drug

Logistic (%)

Hyperbolic (%)

Straight (%)

Exponential (%)

Linear (%)

Noise-dominant (%)

CIS

9(9.7)

11(33.3)

0

1(50.0)

3(23.1)

5(11.6)

5FU

5(5.4)

7(21.2)

3(33.3)

0

3(23.1)

11(25.6)

CPT

10(10.8)

3(9.1)

1(11.1)

0

1(7.7)

5(11.6)

SN38

11(11.8)

0(0.0)

0

0

2(15.4)

8(18.6)

DTX

18(19.4)

3(9.1)

1(11.1)

1(50.0)

0

5(11.6)

PXL

22(23.7)

1(3.0)

1(11.1)

0

1(7.7)

4(9.3)

OXP

3(3.2)

0(0.0)

0

0

0

0

EPS

3(3.2)

1(3.0)

0

0

0

0

GEM

1(1.1)

1(3.0)

0

0

1(7.7)

0

5FU + LEU

0(0)

2(6.1)

0

0

1(7.7)

0

CIS + 5FU

4(4.3)

3(9.1)

1(11.1)

0

0

1(2.3)

MTX

3(3.2)

0

0

0

1(7.7)

3(7.0)

5FU + MTX

1(1.1)

0

1(11.1)

0

0

0

EPI

0

0

1(11.1)

0

0

0

CBP

0

1(3.0)

0

0

0

0

5FU + DTX

1(1.1)

0

0

0

0

0

5FU + SN38

1(1.1)

0

0

0

0

0

DXR

1(1.1)

0

0

0

0

0

VIN

0

0

0

0

0

1(2.3)

Curve Fractionb

93(48.2)

33(17.1)

9(4.7)

2(1.0)

13(6.7)

43(22.2)

  1. a% indicates fraction per curve type; b% indicates fraction of all 193 curve types.