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Table 1 Non-iatrogenic skin metastasis from hepatocellular carcinoma described in the literature the last 10 years.

From: Haematogenous abdominal wall metastasis of differentiated, alpha-fetoprotein-negative hepatocellular carcinoma after previous antiandrogen therapy within a site of lipoma manifestation since childhood

Reference N Sex Age Localisation Seeding AFP ng/ml Appearance Hepatitis
Jegou et al. (2004) [11] 1 M 55 left frontal no n.a. painless nodule n.a.
De Agustin et al. (2007) [12] 1 F 65 face no n.a. n.a. n.a.
Hsieh et al. (2007) [13] 1 M 46 left skull no 71 ng/ml soft mass B
Royer et al. (2008) [14] 1 M 74 nose no n.a. pearly purple nodule n.a.
Magana and Gomez et al. (2009) [15] 1 M 41 right cheek no n.a red papule C
Lazaro et al. (2009) [16] 1 M 61 nasal lesion no n.a. excoriated palpule n.a.
Fukushima et al. (2010) [17] 1 M 58 left skull no n.a n.a n.a
Lee et al. (2010) [18] 1 M 49 tip of nose no n.a. dark spot C
Isa et al. (2011) [19] 1 M 81 left nasal alae no normal multilobulated mass negative
Ackerman et al. (2001) [20] 1 M 52 left scapula no 10000 ng/ml hemangio-sarcoma B,C
Braune et al. (2001) [21] 1 M 76 right chest yes n.a. subcutaneous tumor n.a.
Al-Mashat FM (2004) [22] 1 M 60 chest wall n.a. n.a. n.a. n.a.
Amador et al. (2007) [23] 1 M 80 shoulder no n.a. abscess-like B
Terada et al. (2010) [24] 1 M 86 right chest no n.a cutaneous mass C
Suzuki et al. (2003) [25] 1 M 66 abdomen n.a. n.a. subcutaneous nodule C
Lee et al. (2004) [26] 1 M 68 right upper abdomen yes normal red nodule B
Hyun et al. (2006) [27] 1 M 56 left abdomen no 308 ng/ml n.a. B
Nggada et al. (2006) [28] 1 M 53 chest, back abdomen, no negative nodules B
Martinez Ramos et al. (2007) [29] 1 W 70 subxyphoid region yes 324000 ng/ml violaceous cutaneous mass C
Rowe et al. (2007) [30] 1 W 72 abdominal wall yes n.a. nodule no
Özdil et al. (2009) [31] 1 M 76 right abdomen yes 1860 ng/ml subcutaneous tumor B
Chen et al. (2011) [32] 1 F 69 abdominal wall yes 275-1217 ng/ml n.a C
Fang et al. (2001) [33] 1 M 49 back, hands, feet no n.a. reddish-blue papules n.a.
Kanitakis et al. (2003) [34] 1 F 50 right arm no increased n.a. n.a.
Nagaoka et al. (2004) [35] 1 F 77 right waist yes 8 ng/ml reddish papules n.a.
Masannat et al. (2007) [36] 1 M 63 left calf no 5 ng/ml like soft-tissue sarcoma n.a.
  1. (AFP, alpha-fetoprotein; n.a.: not applicable).