Table 1 Overview of clinical data in 200 patients who underwent right sided colon cancer surgery
Group I ( n = 58) | Group II ( n = 27) | Group III ( n = 115) | P value | |||
|---|---|---|---|---|---|---|
Patient characteristic | Age (years) | ≤65 | 38 (66.7%) | 16 (59.3%) | 52 (45.2%) | |
>65 | 19 (33.3%) | 11 (40.7%) | 63 (54.8%) | 0.007 | ||
Gender | Male | 26 (44.8%) | 13 (48.1%) | 56 (48.7%) | ||
Female | 32 (55.2%) | 14 (51.9%) | 59 (51.3%) | 0.641 | ||
ASA | 1 | 41 (70.7%) | 13 (48.1%) | 64 (55.7%) | ||
2 | 15 (25.9%) | 13 (48.1%) | 46 (40.0%) | |||
3 | 2 (3.4%) | 1 (3.7%) | 5 (4.3%) | 0.114 | ||
BMI (kg/m2) | Mean ± S.D. | 20.7 ± 3.9 | 22.4 ± 2.5 | 22.4 ± 3.3 | 0.001 | |
Operative procedure | Operation method | RHC | 45 (77.6%) | 19 (70.4%) | 75 (65.2%) | |
ERHC | 13 (22.4%) | 8 (29.6%) | 40 (34.8%) | 0.096 | ||
Approach | Open | 58 (100%) | 15 (55.6%) | 34 (29.6%) | ||
Lap | - | 12 (44.4%) | 81 (70.4%) | <0.001 | ||
Vessel ligation | Low | 6 (26.1%) | 3 (17.6%) | 4 (3.7%) | ||
High | 17 (73.9%) | 14 (82.4%) | 103 (96.3%) | <0.001 | ||
Macroscopic feature | Location | Cecum | 12 (20.7%) | 11 (40.7%) | 17 (14.8%) | |
Ascending | 25 (43.1%) | 9 (33.3%) | 57 (49.6%) | |||
H flexure | 20 (34.5%) | 7 (25.9%) | 23 (20.0%) | |||
prox T | 1 (1.7%) | 0 | 18 (15.7%) | 0.097 | ||
Tumor size | ≤6.5 | 34 (58.6%) | 17 (63.0%) | 61 (53.5%) | ||
>6.5 | 24 (41.4%) | 10 (37.0%) | 53 (46.5%) | 0.467 | ||
Mean ± S.D. | 6.5 ± 2.6 | 6.6 ± 3.2 | 6.6 ± 2.7 | 0966 | ||
Microscopic feature | Stage | II | 40 (69.0%) | 18 (66.7%) | 64 (56.1%) | |
III | 18 (31.0%) | 9 (33.3%) | 50 (43.9%) | 0.090 | ||
Pathologic T | 2 | 2 (3.4%) | 1 (3.7%) | 2 (1.8%) | ||
3 | 47 (81.0%) | 24 (88.9%) | 100 (87.7%) | |||
4 | 9 (15.5%) | 2 (7.4%) | 12(10.5%) | 0.651 | ||
Pathologic N | 0 | 36 (62.1%) | 18 (66.7%) | 64 (56.1%) | ||
1 | 15 (25.9%) | 5 (18.5%) | 31 (27.2%) | |||
2 | 7 (12.1%) | 4 (14.8%) | 19 (16.7%) | 0.345 | ||
Differentiation | Well | 21 (36.2%) | 16 (59.3%) | 17 (14.9%) | ||
Moderately | 19 (32.8%) | 6 (22.2%) | 85 (74.6%) | |||
Poorly | 11 (19.0%) | 3 (11.1%) | 9 (7.9%) | |||
Mucinous | 7 (12.1%) | 2 (7.4%) | 3 (2.6%) | 0.685 | ||
Lymphatic invasion | No | 10 (35.7%) | 15 (62.5%) | 88 (77.2%) | ||
Yes | 18 (64.3%) | 9 (37.5%) | 26 (22.8%) | <0.001 | ||
Venous invasion | No | 25 (89.3%) | 22 (91.7%) | 111 (97.4%) | ||
Yes | 3 (10.7%) | 2 (8.3%) | 3 (2.6%) | 0.051 | ||
Perineural invasion | No | 25 (86.2%) | 22 (91.7%) | 97 (85.1%) | ||
Yes | 4 (13.8%) | 2 (8.3%) | 17 (14.9%) | 0.708 | ||
Retrieved LN | <12 | 4 (6.9%) | 10 (37.0%) | 22 (19.3%) | ||
≥12 | 54 (93.1%) | 17 (63.0%) | 92 (80.7%) | 0.103 | ||
Additional treatment | Adjuvant CTx | No | 15 (26.3%) | 1 (3.8%) | 17 (14.9%) | |
Yes | 42 (73.7%) | 25 (96.2%) | 97 (85.1%) | 0.105 | ||
Perioperative course | OP time(mins) | Mean ± S.D. | 199.5 ± 83.4 | 308.5 ± 109.9 | 298.7 ± 86.8 | <0.001 |
Intraoperative Cx | No | 58 (100%) | 26 (96.3%) | 111 (96.5%) | ||
Yes | 0 | 1 (3.7%) | 4 (3.5%) | 0.189 | ||
Intraoperative TF (mL) | Mean ± S.D | 361.6 ± 636.4 | 120.4 ± 243.9 | 83.3 ± 224.8 | <0.001 | |
Postoperative Cx | No | 45 (77.6%) | 22 (81.5%) | 102 (88.7%) | ||
Yes | 15 (22.4%) | 5 (18.5%) | 13 (11.3%) | 0.052 | ||
Postoperative TF (mL) | Mean ± S.D | 156.9 ± 362.9 | 129.6 ± 233.8 | 164.5 ± 250.7 | 0.850 | |
Reoperation | No | 56 (96.6%) | 26 (96.3%) | 114 (99.1%) | ||
Yes | 2 (3.4%) | 1 (3.7%) | 1 (0.9%) | 0.223 | ||
ICU stay (days) | mean ± S.D | 4.3 ± 3.9 | 4.7 ± 3.0 | 1.9 ± 1.5 | <0.001 | |
Hospital stay (days) | mean ± S.D | 23.5 ± 11.4 | 17.6 ± 4.2 | 13.9 ± 6.9 | <0.001 | |
Serology | Preoperative CEA (ng/mL) | ≤5 | 24 (66.7%) | 18 (72.0%) | 68 (65.4%) | |
>5 | 12 (33.3%) | 7 (28.0%) | 36 (34.6%) | 0.790 | ||
Postoperative CEA(ng/mL) | ≤5 | 18 (85.7%) | 13 (92.9%) | 76 (85.4%) | ||
>5 | 3 (14.3%) | 1 (7.1%) | 13 (14.6%) | 0.818 |