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Table 2 Univariate and multivariate analysis of prognostic indicators on overall survival for colorectal cancer patients

From: The impact on clinical outcome of high prevalence of diabetes mellitus in Taiwanese patients with colorectal cancer

Parameters

Number

Univariate analysis Hazard ratio (95% CI)

P value

Multivariate analysis Hazard ratio (95% CI)

P value

DM (yes/no)

283/914

1.02(0.81-1.27)

.888

0.94(0.71-1.24)

0.642

Age (≥65/<65)years

632/565

1.33(1.09-1.62)

.004

1.36(1.05-1.76)

0.021

Sex (Male/Female)

674/523

1.13(0.93-1.37)

.221

1.09(0.85-1.40)

0.491

Location (Rectum/Colon)

369/828

0.89(0.65-1.00)

.048

0.80(0.61-1.05)

0.114

Tumor size (≥5/<5)cm

518/679

1.47(1.21-1.78)

< .001

1.12(0.87-1.44)

0.368

BMIa (<22/≥22) kg/M2

394/803

1.39(1.13-1.70)

.001

1.14(0.88-1.48)

0.311

Albumin (<3.5/≥3.5)gm/dl

476/721

1.83(1.48-2.25)

< .001

1.32(1.02-1.70)

0.037

Histology (PD/MD + WDb)

135/1062

1.93(1.48-2.52)

< .001

1.45(1.04-2.02)

0.030

AJCCc stage (III&IV/I&II)

565/632

3.36(2.73-4.14)

< .001

1.32(1.02-1.70)

0.037

Pre-op CEAd (≥5/<5) ng/ml

559/638

2.86(2.31-3.53)

< .001

1.26(0.93-1.70)

0.143

Post-op CEAd (≥5/<5) ng/ml

338/859

5.30(4.30-6.54)

< .001

3.61(2.80-4.64)

< 0.001

Vascular invasion (yes/no)

395/802

2.79(2.28-3.41)

< .001

1.58(1.22-2.05)

< 0.001

Perineurial invasion (yes/no)

447/750

2.27(1.86-2.78)

< .001

1.79(1.39-2.30)

< 0.001

  1. a BMI Body mass index.
  2. b PD Poorly differentiated, MD Moderately differentiated, WD Well differentiated.
  3. c AJCC American Joint Commission on Cancer.
  4. d CEA Carcinoembryonic antigen.