Table 1 Previous Reported cases of PCSRCC

Moll et al (1990)

50

Post-coital vaginal bleeding, menometrorrhagia

III (metastases of ovary and lymph nodes)

Not done

Not done

Surgery and whole pelvic irradiation

DOD 10 mo

Mayorga et al (1997)

68

74

Post-coital bleeding

Post-menopausal bleeding

Ib

Ib

Not done

Not done

Not done

Not done

Preoperative chemotherapy and surgery

Surgery

NED 35 mo

NED 25 mo

Haswani et al (1998)

33

38

Asymptomatic AGC-NOS on a routine vaginal smear)

Post-coital vaginal bleeding

In both cases previous cervical condylomas

Adenosquamous ca, III, N1

AIS/HSIL

Ib N1

HPV type 18 by PCR

Not done

-/

--/-

Palliative radio and chemotherapy

Surgery and radiotherapy

DOD 10 mo

NED 18 mo

Cardosi et al. (1999)

53

Perimenopausal bleeding

neuroendocrine differentiation

Ib

Not done

+/+

Surgery, radiotherapy Chemotherapy

NED 6 mo

Moritani et al (2004)

29

Persistent abnormal genital bleeding

glassy cell component

III b N1

- by immunohistochemistry

-/-

Chemotherapy

NED 6 mo

Insabato et al (2007)

46

Vaginal bleeding

in cervical polypoid lesion

Ib

Not done

Not Done

Surgery radiotherapy Chemotherapy

NED 3 yrs

Suárez-Peñaranda (2007)

80

Vaginal discharge

neuroendocrine differentiation IIIb

Not done

Not Done

Radiotherapy/Chemotherapy

DOD 18 mo

McCluggage WG et al (2008)

NR

Two cases NR

Foci of signet-ring cell in the usual type of cervical adenocarcinoma

Diffuse positivity to P16

Not done

Not Done

NR

NR

Versas E et al

(2009)

36

43

Thromboembolic events (Trousseau Syndrome)Metastases of lung and lymph nodes

+ HPV by in situ

hybridization

-/-

-/-

Chemotherapy

Chemotherapy

DOD 7 wks

DOD 2 mo

Balci et al (2010)

53

Post-menopausal bleeding

(0% of neoplasms with SRC II b3x 5 × 2 parametrio N1

HPV type 18

-/-

Surgery

NR