Table 1 Serum tumor markers and clinicopathologic factors of the patients
From: Prognostic significance of tumor markers in T4a gastric cancer
Factors (n) | AFP(+) n (%) | P | CEA(+) n (%) | P | CA19-9(+) n (%) | P | CA50(+) n (%) | P |
|---|---|---|---|---|---|---|---|---|
Sex | 0.408 | 0.029 | 0.213 | 0.242 | ||||
Male (192) | 13 (6.8) | 37 (19.3) | 67 (34.9) | 61 (31.8) | ||||
Female (81) | 3 (3.7) | 7 (8.6) | 22 (27.2) | 20 (24.7) | ||||
Age (years) | 0.053 | 0.779 | 0.047 | 0.017 | ||||
≤40 (26) | 4 (15.4) | 3 (11.5) | 13 (50.0) | 13 (50.0) | ||||
>40 (247) | 12 (4.9) | 41 (16.6) | 76 (30.8) | 68 (27.5) | ||||
Tumor site | 0.153 | 0.014 | 0.011 | 0.004 | ||||
Upper (90) | 5 (5.6) | 16 (17.8) | 31 (34.4) | 31 (34.4) | ||||
Middle (52) | 3 (5.8) | 5 (9.6) | 19 (36.5) | 15 (28.9) | ||||
Lower (124) | 6 (4.8) | 19 (15.3) | 33 (26.6) | 29 (23.4) | ||||
≥Two-third (7) | 2 (28.6) | 4 (57.1) | 6 (85.7) | 6 (85.7) | ||||
Tumor size | 0.063 | 0.812 | 0.102 | 0.014 | ||||
≤6 (178) | 7 (3.9) | 28 (15.7) | 52 (29.2) | 44 (24.7) | ||||
>6 (95) | 9 (9.5) | 16 (16.8) | 37 (38.9) | 37 (38.9) | ||||
Borrmann type | 0.010 | 0.365 | 0.086 | 0.066 | ||||
I (15) | 0 (0.0) | 2 (13.3) | 4 (26.7) | 3 (20.0) | ||||
II (8) | 1 (12.5) | 0 (0.0) | 4 (50.0) | 2 (25.0) | ||||
III (228) | 10 (4.4) | 36 (15.8) | 69 (30.3) | 64 (28.1) | ||||
IV (22) | 5 (22.7) | 6 (27.3) | 12 (54.6) | 12 (54.6) | ||||
N stage | 0.065 | 0.001 | 0.000 | 0.000 | ||||
N0 (49) | 0 (0.0) | 3 (6.1) | 7 (14.3) | 6 (12.2) | ||||
N1 (49) | 1 (2.0) | 6 (12.2) | 14 (28.6) | 14 (28.6) | ||||
N2 (52) | 4 (7.7) | 3 (5.8) | 10 (19.2) | 9 (17.3) | ||||
N3 (123) | 11 (8.9) | 32 (26.0) | 58 (47.2) | 52 (42.3) | ||||
Nervous invasion | 0.156 | 0.520 | 0.051 | 0.294 | ||||
+ (197) | 9 (4.6) | 30 (15.2) | 71 (36.0) | 62(31.5) | ||||
- (76) | 7 (9.2) | 14 (18.4) | 18 (23.7) | 19 (25.0) | ||||
Lymphovascular invasion | 0.399 | 0.212 | 0.004 | 0.085 | ||||
+ (196) | 10 (5.1) | 35 (17.9) | 74 (37.8) | 63(32.7) | ||||
- (77) | 6 (7.8) | 9 (11.7) | 15 (19.5) | 17 (22.1) |