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Table 1 Clinicopathological characteristics and univariate analysis of 211 patients

From: Factors predictive of papillary thyroid micro-carcinoma with bilateral involvement and central lymph node metastasis: a retrospective study

Characteristics

Total (n = 211)

Bilateral PTMC

(n = 54)

Unilateral PTMC

(n = 157)

P value

Gender(M/F)

32/179

8/46

24/133

0.934

Age ± SD (years)

49 ± 11

49 ± 10

48 ± 11

0.679a

≥45/<45

143/68

38/16

105/52

0.636

≥50/<50

97/114

23/31

74/83

0.564

Primary tumor size ± SD (mm)

5.8 ± 2.7

6.8 ± 2.6

5.5 ± 2.7

0.001a,b

≥5/<5

144/67

44/10

100/57

0.015 b

≥7/<7

81/130

28/26

53/104

0.018 b

Multifocality (%)

25 (11.8)

21 (38.9)

4 (2.6)

<0.001b

ETE (%)

10 (4.7)

5 (9.3)

5 (3.2)

0.128c

T stage (T1/2:T3/4)

201/10

49/5

152/5

0.128c

With HT (%)

59 (28.0)

20 (37.0)

39 (24.8)

0.085

Preoperative tumor size (mm)

6.1 ± 2.9

7.1 ± 2.7

5.8 ± 2.8

0.005a,b

≥5/<5

152/59

46/8

106/51

0.013 b

≥7/<7

85/126

29/25

56/101

0.020 b

Preoperative multifocality (%)

19 (8.6)

16 (29.6)

3 (1.9)

<0.001b,c

  1. aCalculated using two-tailed student t test.
  2. bStatistically significant (P <0.05).
  3. cCalculated using Fisher exact test, others calculated using chi-square test.
  4. ETE, extrathyroidal extension; HT,Hashimoto thyroiditis; PTMC, papillary thyroid microcarcinoma.