From: Problems of primary T-cell lymphoma of the thyroid gland -A case report
References* | Age/gender | Presentation | Chronic thyroiditis | HTLV-1 | Histology | Molecular Diagnosis | Diagnostic intervention | Therapy | prognosis |
---|---|---|---|---|---|---|---|---|---|
[3] 1977 | 73/F | N/A | N/A | S + R | alive at 24 months | ||||
[4] 1990 | 79/M | Goiter | N/A | N/A | Diffuse small cleaved | open biopsy | C + R | alive at 4 years | |
[4] 1990 | 80/F | Goiter | (+) | N/A | Diffuse small cleaved | Hemithyroidectomy | S | DUC | |
[5] 1996 | 64/F | Thyroid mass, Hypothyroidism | (+) | (-) | CD2+, CD3+, CD5+, CD45RO+ | TCR-β, TCR-γ rearrangement | Total thyroidectomy | S + C + R | alive at 9 months |
[6] 1997 | 59/F | Goiter | (+) | (-) | CD3+, CD4-, CD8-, CD19- | TCR-δ rearrangement | Open biopsy | C + R | alive at 22 months |
[7] 1999 | 65/M | Thyroid mass, Horseness, dyspasia, | (-) | N/A | CD45RO+, CD45-, vimentin+ | Open biopsy | C + R | died at 11 months | |
[8] 1999 | 39/F | Goiter, fever, dysphonia | (+) | N/A | CD30+, CD45RO+, CD3-, CD20-, CD79a-, CD21- | Open biopsy | C + R | alive at 1 year | |
[9] 2000 | 63/F | Thyroid mass, Hoarseness, dyspnea | (+) | N/A | CD45RO+, CD43+ | Total thyroidectomy | S + C + R | alive at 3 years | |
[10] 2001 | 72/M | Thyroid mass, pressure, difficulty swallowing | (+) | N/A | CD4+ | Right hemithyroidectomy | C + R | alive at 12 months | |
[11] 2005 | 71/F | Thyroid swelling, horseness, goiter | (+) | (-) | CD3+, CD45RO+, CD4+ | TCR-β, TCR-γ rearrangement | Total thyroidectomy | S | alive at 25 months |
[12] 2005 | 86/F | Swelling of neck | (-) | (-) | CD3e+, CD5+, TIA-1+ (T-cell restricted antigen) | TCR-Cβ rearrangement | Left hemithyroidectomy | S | alive at 2 years |
[13] 2007 | 34/M | N/A | (-) | (-) | CD3+, CD5+, CD7-, CD43+, CD45RO+, CD20- | N/A | S + C + R | died at 13 months | |
[14] 2007 | 61/M | Thyroid mass | (+) | (-) | CD3+, CD4+, | TCR-β rearrangement | Open biopsy | C | alive at 4 years |
[14] 2007 | 68/M | Thyroid mass, dyspnea | (+) | (-) | CD3+, CD4+, TCR-ab+ | Open biopsy | C | died at 5 months | |
[15] 2008 | 32/M | Swelling of neck, fatigue, shortness of breath | (-) | N/A | CD3+, | TCR-γ rearrangement(PCR) | Open biopsy | C | alive at 1 year |
present | 70/F | Neck swelling | (+) | (-) | CD3+, CD45RO+, | TCR-β, TCR-γ rearrangement | Total thyroidectomy | S | alive at 20 months |