Table 2 Showing the yield (sensitivity and specificity) and reliability (PPV and NPV) of toluidine blue as compared to frozen section biopsy and histopathological examination
From: A comparative analysis of toluidine blue with frozen section in oral squamous cell carcinoma
| Â | Â | Sensitivity | Specificity | PPV | NPV |
|---|---|---|---|---|---|
Overall | Â | 100% | 97.1% | 27.2% | 100% |
T-Stage | Â | Â | Â | Â | Â |
T-I | Â | - | 98.1% | - | 100% |
T-II | Â | 100% | 100% | 100% | 100% |
T-III | Â | 100% | 98.1% | 50% | 100% |
T-IV | Â | 100% | 91.8% | 14% | 100% |
Tumor | Site | Â | Â | Â | |
Buccal | mucosa | 100% | 97.3% | 25% | 100% |
Tongue | Â | 100% | 98.4% | 50% | 100% |
RetromolarTrigone | Â | - | 96% | - | 100% |
Lower | alveolus | 100% | 94.1% | 33.3% | 100% |
Upper | alveolus | - | 96% | - | 100% |
Floor of mouth | - | 100% | - | 100% | |