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Table 2 Correlation between combined p53 mutation and p14ARF, DAPK, and/or ASC/TMS1 methylation with pathologic biology in cholangiocarcinoma

From: Correlation between promoter methylation of p14ARF, TMS1/ASC, and DAPK, and p53 mutation with prognosis in cholangiocarcinoma

   combined p53 mutation and p14ARF, DAPK, and/or ASC/TMS1 methylation
Pathologic character cases positive positive ratio (%) P-value
Pathologic type     
   Tubular carcinoma 18 5 27.8  
   Papillary carcinoma 9 1 11.1  
   Mucoid carcinoma 4 4 100.0  
   Non-differentiated 5 4 80.0 < 0.05
   carcinoma     
Differentiation     
   Well -Moderate 25 6 24.0  
   Poor 11 8 72.7 < 0.05
Invasion     
   T1 16 2 12.5  
   T2 10 4 40.0  
   T3 10 8 80.0 < 0.05
Lymph node metastasis     
   N0 3 0 0  
   N1 33 14 42.4 > 0.05