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Table 4 Correlations of the presence of K-ras and B-raf mutations (exon 15) with immunohistochemical results in patients for whom staining data were available.

From: ERK/pERK expression and B-raf mutations in colon adenocarcinomas: correlation with clinicopathological characteristics

 

K-ras Mutation

B-raf Exon 15 mutation

 

Absent

Present

p

Absent

Present

p

ERK nuclear expression (n = 55)

      

Absent

4

3

 

7

0

 

Present

37

11

0.354

44

4

0.99

ERK cytoplasmic expression (n = 55)

      

Absent

3

2

 

4

1

 

Present

38

12

0.592

47

3

0.325

ERK nuclear and cytoplasmic expression (n = 55)

      

Absent

7

5

 

11

1

 

Present

34

9

0.259

40

3

0.99

pERK nuclear expression (n = 65)

      

Absent

11

3

 

13

1

 

Present

24

7

0.99

27

4

0.99

pERK cytoplasmic expression(n = 65)

      

Absent

27

7

 

29

5

 

Present

8

3

0.687

11

0

0.313

pERK nuclear and cytoplasmic expression (n = 65)

      

Absent

29

8

 

32

5

 

Present

6

2

0.99

8

0

0.357

hMLH1 expression (n = 63)

      

Reduced

13

5

 

15

3

 

Preserved

33

12

0.99

41

4

0.397

hMSH2 expression (n = 53)

      

Reduced

12

6

 

13

5

 

Preserved

24

11

0.99

32

3

0.104

  1. Results of Fischer's exact test.