Figure 1From: ERK/pERK expression and B-raf mutations in colon adenocarcinomas: correlation with clinicopathological characteristicsA. Grade 1, stage I colorectal carcinoma, displaying minimal nuclear pERK staining. B. Grade 3, stage III colorectal carcinoma, displaying increased nuclear pERK staining. C, D. ERK nuclear and cytoplasmic immunoreactivity in grade 1, stage II (C) and grade 3, stage III with production of extra-cellular mucin (D).Back to article page