Table 4 Multivariate Cox regression model of prognostic covariates in 264 patients with oral cavity squamous cell carcinoma regarding disease-free and overall survival
From: Cyclin D1 overexpression and poor clinical outcomes in Taiwanese oral cavity squamous cell carcinoma
| Â | DFS | Â | OS | Â |
|---|---|---|---|---|
Characteristic | HR (95% CI) | P value | HR (95% CI) | P value |
Age (years old) | Â | Â | Â | Â |
   < 50 | 1 |  | 1 |  |
   ≥ 50 | 1.076 (0.755 - 1.534) | 0.685 | 1.108 (0.769 - 1.595) | 0.582 |
Differentiation | Â | Â | Â | Â |
   Well | 1 |  | 1 |  |
   Moderate/poor | 1.092 (0.759 - 1.571) | 0.636 | 1.334 (0.904 - 1.968) | 0.146 |
Primary tumor | Â | Â | Â | Â |
   T1/T2 | 1 |  | 1 |  |
   T3/T4 | 1.176 (0.822 - 1.684) | 0.375 | 1.462 (1.005 - 2.127) | 0.047 |
Nodal status | Â | Â | Â | Â |
   (-) metastasis, (-) ECS | 1 |  | 1 |  |
   (+) metastasis, (-) ECS | 0.929 (0.562 - 1.536) | 0.775 | 1.128 (0.672 - 1.892) | 0.649 |
   (+) metastasis, (+) ECS | 2.199 (1.446 - 3.343) | < 0.001 | 2.627 (1.711 - 4.035) | < 0.001 |
Overexpression of Cyclin D1 protein | Â | Â | Â | Â |
   No | 1 |  | 1 |  |
   Yes | 1.540 (1.068 - 2.222) | 0.021 | 1.702 (1.168 - 2.480) | 0.006 |