Table 3 Univariate regression model of prognostic covariates in 264 patients with oral cavity squamous cell carcinoma regarding disease-free and overall survival
From: Cyclin D1 overexpression and poor clinical outcomes in Taiwanese oral cavity squamous cell carcinoma
| Â | DFS | Â | OS | Â |
|---|---|---|---|---|
Characteristic | HR (95% CI) | P value | HR (95% CI) | P value |
Age (years old) | Â | Â | Â | Â |
   < 50 | 1 |  | 1 |  |
   ≥ 50 | 1.038 (0.731 - 1.472) | 0.836 | 1.118 (0.779 - 1.605) | 0.545 |
Differentiation | Â | Â | Â | Â |
   Well | 1 |  | 1 |  |
   Moderate/poor | 1.232 (0.864 - 1.758) | 0.250 | 1.571 (1.074 - 2.300) | 0.020 |
Primary tumor | Â | Â | Â | Â |
   T1/T2 | 1 |  | 1 |  |
   T3/T4 | 1.301 (0.918 - 1.843) | 0.138 | 1.617 (1.123 - 2.328) | 0.010 |
Nodal status | Â | Â | Â | Â |
   (-) metastasis, (-) ECS | 1 |  | 1 |  |
   (+) metastasis, (-) ECS | 1.042 (0.639 - 1.699) | 0.870 | 1.349 (0.813 - 2.238) | 0.247 |
   (+) metastasis, (+) ECS | 2.550 (1.726 - 3.765) | < 0.001 | 3.391 (2.265 - 5.077) | < 0.001 |
Overexpression of cyclin D1 protein | Â | Â | Â | Â |
   No | 1 |  | 1 |  |
   Yes | 1.710 (1.202 - 2.434) | 0.002 | 1.970 (1.371 - 2.831) | < 0.001 |