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Table 2 Demographics, Tumor Localizations, Operation Technique, Intra- and Postoperative Parameters, Complications and Pathological Features in Patients Who Underwent Single Organ and Multivisceral Resections

From: Results after multivisceral resections of locally advanced colorectal cancers: an analysis on clinical and pathological t4 tumors

 

Single organ resections (n = 264)

Multivisceral resections (n = 90)

p

Demographics

   

   Age

59.7 ± 13.7

59.4 ± 13.9

0.871

   Gender (males)

168 (63.3)

42 (46.7)

0.005

Localization (Colon/Rectum)

116 (48.5)/148 (51.5)

43 (56.7)/47 (43.3)

0.527

Preoperative metastasis

32 (12.1)

11 (12.2)

0.980

   Synchrone metastasectomy

10 (3.8)

4 (4.4)

0.759

Operation technique

   

   Conventional/laparoscopic

110 (41.7)/154 (58.3)

54 (60.0)/36 (40.0)

0.003

   Conversion (%)

25/154 (16.2)

15/36 (41.7)

0.001

Intra- and Postoperative Parameters

   

Operation time (min)

(n = 252) 203.0 ± 53.4

(n = 83) 256.4 ± 77.0

0.0001

Intraoperative bleeding (ml)

(n = 213) 250 0[1-4000]

(n = 68) 450 [100-2700]

0.0001

Total transfusion

   

   Rate

119/256 (47.4)

61/88 (68.5)

0.0001

   Amount

0 (0-12)

2 (0-26)

0.001

Synchrone metastasectomy

10 (3.8)

4 (4.4)

0.759

Length of hospital stay

8.6 ± 6.8

9.0 ± 4.9

0.652

Complications

(n = 264)

(n = 90)

 

   Surgical site infection

13 (4.9)

6/90 (6.6)

0.590

Wound infection

6 (2.3)

3 (3.3)

 

Evisceration

5 (1.9)

2 (2.2)

 

Intraabdominal abscess

2 (0.8)

1 (1.1)

 

   Fistula

16 (6.0)

5 (5.5)

0.831

Anastomotic

14 (5.3)

2 (2.2)

 

Urinary

1 (0.4)

2 (2.2)

 

   Biliary

1 (0.4)

1 (1.1)

 

   Anastomotic leakage

14 (5.3)

2 (2.2)

0.378

   Ileus

11 (4.2)

5 (5.5)

0.568

   Nonsurgical

5 (1.9)

3 (3.3)

0.429

   Intrabdominal hemorrhage

7 (2.7)

4 (4.4)

0.483

   Urinary retantion/leakage

2 (0.8)

1 (1.1)

0.999

   Missed bowel injury

1 (0.4)

1 (1.1)

0.449

   Reoperation

5 (2.0)

2 (1.1)

0.999

Intrabdominal hemorrhage

2 (0.8)

1 (1.1)

 

Anastomotic leakage

2 (0.8)

0 (0)

 

Missed bowel injury

1 (0.4)

1 (1.1)

 

   Overall

55 (20.9)

22 (24.4)

0.516

30-day mortality

11 (4.2)

4 (4.4)

0.999

T Stage

  

0.0001

pT0*/pT1/pT2/pT3/pT4

16 (6.1)/12 (4.5)/37 (14)/199 (75.4)/0

1 (1.1)/1 (1.1)/9 (10)/48 (53.3)/31 (34.4)

 

Harvested lymph nodes

13.7 ± 7.3

16.0 ± 9.6

0.043

N Stage

  

0.227

pN (negative)/(positive)

148 (56.1)/116 (43.9)

54 (60)/44 (40)

 

Vascular invasion

103 (39.0)

43 (47.7)

0.363

Perineural invasion

116 (43.9)

54 (60.0)

0.043

Differentiation

  

0.227

Poorly/Moderately/Well/Undetermined or missed

28 (10.6)/208 (78.8)/12 (4.5)/16 (6.1)

8 (8.9)/77 (85.6)/4 (4.4)/1 (1.1)

 

Positive surgical margin (R1-R2 resection)

2 (0.8)

2 (2.2)

0.268

  1. * includes only pT0 rectal tumors after neoadjuvant chemo-radiation therapy (complete response)