Clinicopathologic characteristics | Very high pre-ALP (n= 52) | High pre-ALP (n= 76) | Normal pre-ALP (n= 49) | P value |
---|---|---|---|---|
Gender | ||||
Male | 35 | 50 | 32 | 0.831 |
Female | 17 | 26 | 17 | |
Primary location | ||||
Humerus | 6 | 2 | 4 | 0.005 |
Radius | 0 | 1 | 0 | |
Femur | 36 | 40 | 17 | |
Tibia | 7 | 28 | 17 | |
Fibula | 3 | 2 | 8 | |
Others | 0 | 3 | 3 | |
Histological type | ||||
Osteoblastic | 40 | 45 | 24 | < 0.01 |
Chondroblastic | 8 | 12 | 5 | |
Fibroblastic | 1 | 9 | 6 | |
Dilated blood vessels | 3 | 5 | 3 | |
Others | 0 | 5 | 11 | |
Tumor size | ||||
< 6 cm | 14 | 35 | 26 | 0.008 |
≥ 6 cm | 38 | 41 | 23 | |
Surgery type | ||||
Amputation | 24 | 35 | 26 | 0.268 |
Limb sparing | 28 | 41 | 23 | |
Post-operative chemotherapy | ||||
No standard a | 40 | 54 | 20 | < 0.01 |
Standard b | 12 | 22 | 29 | |
Lung metastasis | ||||
Yes | 18 | 16 | 6 | 0.007 |
No | 34 | 60 | 43 | |
Local recurrence | ||||
Yes | 4 | 7 | 3 | 0.782 |
No | 48 | 69 | 46 | |
Survival status | ||||
Alive | 14 | 35 | 32 | < 0.01 |
Dead | 38 | 41 | 17 |