Table 1 Clinical features of study subjects and tumor characteristics
From: Urinary metabolomic signature of esophageal cancer and Barrett’s esophagus
Number of subjects (n) | Esophageal Ca (44) | Controls (44) | p | Barrett's (31) | Controls (31) | p |
|---|---|---|---|---|---|---|
Age [median (range)] | 63 (40-86) | 62 (41-84) | 0.824 | 64.5 (38-81) | 64.5 (36-80) | 1.000 |
Gender (male/female) | 32/12 | 32/12 | 1.000 | 19/12 | 19/12 | 1.000 |
TNM Stage | ||||||
Ia/b | 3/44 (6.8%) | - | - | - | - | - |
IIa/b | 11/44 (25%) | - | - | - | - | - |
IIIa | 10/44 (22.7%) | - | - | - | - | - |
IIIb | 6/44 (13.6%) | |||||
IIIc | 6/44 (13.6%) | |||||
Unknown | 8/44 (18.2%) | - | - | - | - | - |
Histologic Type | - | - | ||||
Esophageal Adenocarcinoma | 32/44 (72.7%) | - | - | - | - | - |
Squamous Cell Carcinoma | 11/44 (25%) | - | - | - | - | - |
Poorly Differentiated | 11/44 (2.3%) | |||||
Histologic Grade | - | - | ||||
1 | 4/44 (9.1%) | - | - | - | - | - |
2 | 17/44 (38.6%) | - | - | - | - | - |
3 | 17/44 (38.6%) | - | - | - | - | - |
Unavailable | 6/44 (13.6%) | - | - | - | - | - |
Location | - | - | ||||
Cervical | 1/44 (2.3%) | - | - | - | - | - |
Upper Thoracic | 1/44 (2.3%) | - | - | - | - | - |
Middle Thoracic | 8/44 (18.2%) | |||||
Lower Thoracic/EGJ | 35/44 (79.5%) | |||||
Resectable | 27/44 (61.4%) | - | - | - | - | - |
Unresectable | 17/44 (38.6%) | - | - | - | - | - |
Barrett's Esophagus | ||||||
Short segment (<3cm) | 24/31 (77.4%) | |||||
Long segment (≥3cm) | 8/31 (25.8%) | |||||
Dysplasia | ||||||
Low grade | 1/31 (3.2%) | |||||
High grade | 0/31 (0%) | |||||
Average time from initial diagnosis (yr) | 2.3 | |||||
Weight Loss (≥5%) | - | - | ||||
Yes | 30/44 (68.2%) | - | - | - | - | - |
No | 6/44 (13.6%) | - | - | - | - | - |
Unavailable | 8/44 (18.2%) | - | - | - | - | - |