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Table 3 Effect of tumor markers and clinical factors on tumor recurrence

From: Prognostic value of expression of molecular markers in adenoid cystic cancer of the salivary glands compared with lymph node metastasis: a retrospective study

Marker/factor

 

HR

95% CI

P

c-kit

0, 1+

1

0.402 - 2.45

0.987

 

2+, 3+

0.993

  

EGFR

0

0.862

0.349 - 2.129

0.747

 

1+, 2+

1

  

VEGF

0, 1+

0.958

0.386 - 2.377

0.927

 

2+, 3+

1

  

Sex

Male

1

0.195 - 1.212

0.122

 

Female

0.486

  

Site

Submandibular gland

1

  
 

Parotid gland

0.392

0.18 - 1.45

0.153

 

Minor salivary gland

0.81

0.266 - 2.468

0.71

Histology

Tubular

1

  
 

Cribriform

0.513

0.061 - 4.283

0.538

 

Solid

3.727

0.423 - 32.813

0.236

 

Indeterminate

0.446

0.053 - 3.781

0.459

Perineural invasion

Negative

1

0.384 - 2.405

0.932

 

Positive

0.961

  

Resection margin

Negative

1

0.224 - 1.406

0.217

 

Positive

0.561

  

Lymph node involvement

Negative

1

2.178 - 19.982

<0.001

 

Positive

6.597

  

Treatment

Surgery only

1

  
 

Surgery + RT

0.89

0.192 - 4.122

0.881

 

Surgery + CCRT

4.002

0.793 - 20.197

0.093

Age (years)

 

0.949

0.902 - 0.998

0.071

Tumor size (cm)

 

0.864

0.566 - 1.318

0.498

  1. CCRT, concurrent chemoradiation therapy; CI, confidence interval; EGFR, epidermal growth factor receptor; HR, hazard ratio; RT, radiation therapy; VEGF, vascular endothelial growth factor.