MSH2 and CXCR4 involvement in malignant VIPoma

Table 4 Microsatellite markers used for MSI and LOH detection in pancreatic tumor tissue, liver metastasis tissue, and normal liver tissue

		Pancreatic tumor		Liver metastasis		Normal liver
Marker	Localization		AP ratio		AP ratio		AP ratio
D1S104	1q21-23	LOH	0.2	LOH	0.49	MSS	>0.7
D2S443	2p13	LOH	0.19	LOH	0.42	MSS	>0.7
BAT26	2p16	MSS	>0.7	MSS	>0.7	MSS	>0.7
D2S123	2p16	LOH	0.21	LOH	0.45	MSS	>0.7
D3S1284	3p12	LOH	0.19	LOH	0.47	MSS	>0.7
BAT25	4q12	MSS	>0.7	MSS	>0.7	MSS	>0.7
D5S326	5q22.2	LOH	0.2	LOH	0.31	LOH	0.32
D16S752	16q22	LOH	0.12	LOH	0.39	MSS	>0.7
D17S250	17q11.2-12	MSS	>0.7	MSS	>0.7	MSS	>0.7
D21S1436	21q21	LOH	0.6	LOH	0.4	LOH	0.59

AP ratio, Allele peak ratio; LOH, Loss of heterozygosity; MSS, Microsatellite stable.

ISSN: 1477-7819