Table 2 Clinicopathological characteristics
From: Undifferentiated-type gastric adenocarcinoma: prognostic impact of three histological types
Variable | PDAC | uMAC | SRC | P- value |
|---|---|---|---|---|
n= 1002 | n= 54 | n= 320 | ||
Age, years (mean ± SD) | 54.6 ± 12.8 | 57.3 ± 12.1 | 52.4 ± 12.0 | 0.003 |
Gender, n (%) | ||||
Male | 605 (60.4) | 35 (64.8) | 187 (58.4) | 0.637 |
Female | 397 (39.6) | 19 (35.2) | 133 (41.6) | |
Multiplicity, n (%) | ||||
Single | 982 (98.0) | 53 (98.1) | 316 (98.8) | 0.612 |
Multiple | 20 (2.0) | 1 (1.9) | 4 (1.3) | |
Tumor location, n (%) | ||||
Upper | 108 (10.8) | 4 (7.4) | 22 (6.9) | 0.184 |
Middle | 392 (39.1) | 17 (31.5) | 141 (44.1) | |
Lower | 452 (45.1) | 31 (57.4) | 139 (43.4) | |
Whole | 50 (5.0) | 2 (3.7 %) | 18 (5.6) | |
Tumor size, cm (mean ± SD) | 5.7 ± 3.7 | 7.1 ± 3.8 | 4.8 ± 3.2 | <0.001 |
Lauren, n (%) | ||||
Intestinal type | 0 (0) | 0 (0) | 0 (0) | <0.001 |
Diffuse type | 782 (78.0) | 37 (68.5) | 290 (90.6) | |
Mixed type | 220 (22.0) | 17 (31.5) | 30 (9.4) | |
Lymphatic invasion, n (%) | ||||
Present | 607 (60.6) | 42 (77.8) | 120 (37.5) | <0.001 |
Absent | 395 (39.4) | 12 (22.2) | 200 (62.5) | |
Vascular invasion, n (%) | ||||
Present | 105 (10.5) | 12 (22.2) | 27 (8.4) | 0.009 |
Absent | 897 (89.5) | 42 (77.8) | 293 (91.6) | |
Perineural invasion, n (%) | ||||
Present | 490 (48.9) | 29 (53.7) | 108 (33.8) | <0.001 |
Absent | 512 (51.1) | 25 (46.3) | 212 (66.3) | |
Depth of invasion, n (%) | ||||
T1 | 248 (24.8) | 3 (5.6) | 164 (51.3) | <0.001 |
T2 | 152 (15.2) | 4 (7.4) | 32 (10.0) | |
T3 | 242 (24.2) | 13 (24.1) | 40 (12.5) | |
T4 | 360 (35.9) | 34 (63.0) | 84 (26.3) | |
Lymph node metastasis, n (%) | ||||
N0 | 422 (42.1) | 9 (16.7) | 201 (62.8) | <0.001 |
N1 | 134 (13.4) | 11 (20.4) | 25 (7.8) | |
N2 | 131 (13.1) | 10 (18.5) | 27 (8.4) | |
N3 | 315 (31.4) | 24 (44.4) | 67 (20.9) | |
Pathological stage, n (%) | ||||
I | 323 (32.2) | 4 (7.4) | 180 (56.3) | <0.001 |
II | 212 (21.2) | 11 (20.4) | 50 (15.6) | |
III | 354 (35.3) | 30 (55.6) | 64 (20.2) | |
IV | 113 (11.3) | 9 (16.7) | 26 (8.1) |