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Figure 3 | World Journal of Surgical Oncology

Figure 3

From: A pure invasive cribriform carcinoma of the breast with bone metastasis if untreated for thirteen years: a case report and literature review

Figure 3

Tumor cells invade into the skin and muscle. (a) Numerous cribriform carcinoma cells present in the dermis of skin. Some tumor cells even infiltrate into the epidermis. Magnified views of box 1 and box 2 are displayed in (b) and (c), respectively. (b) The tumor cells invading the epidermis have grown in a cribriform pattern. (c) The invasive cribriform carcinoma may be the origin of ductal carcinoma in situ, often in a cribriform growth. (d) Some tumor cells invade the muscle. A magnified view is shown in the boxed area d1. The infiltrating carcinoma cells usually display in a cribriform pattern. Scale bars = 5 μm in a and d, 10 μm in b and c, and 20 μm in d1.

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