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Table 3 Cox regression analysis of prognostic factors in colorectal carcinoma

From: Lgr5 is a potential marker of colorectal carcinoma stem cells that correlates with patient survival

Prognostic variables B SE Wald value P value HR 95% CI for HR
Lower Upper
Gender 0.051 0.205 0.063 0.802 1.053 0.705 1.572
Age (years) 0.262 0.130 4.037 0.045 1.299 1.006 1.677
Tumor size 0.031 0.187 0.027 0.869 1.031 0.715 1.487
Histological grade 0.541 0.179 9.184 0.002 1.718 1.211 2.438
Depth of invasion 0.235 0.204 1.325 0.250 1.264 0.848 1.885
Lymph node metastasis −0.043 0.198 0.048 0.824 0.957 0.649 1.412
Distant metastasis 1.383 0.536 6.661 0.010 3.989 1.395 11.405
TNM stage 0.638 0.237 7.285 0.007 1.894 1.191 3.010
Lgr5 expression 1.018 0.274 13.842 0.001 2.768 1.619 4.732
Ki-67 expression 0.819 0.244 11.263 0.001 2.267 1.406 3.657
  1. B, Partial regression coefficient; CI, Confidence interval; HR, Hazard ratio; SE, Standard error.
  2. P<0.05, statistically significant.