Lgr5 is a potential marker of colorectal carcinoma stem cells that correlates with patient survival

Table 3 Cox regression analysis of prognostic factors in colorectal carcinoma

Prognostic variables	B	SE	Wald value	P value	HR	95% CI for HR
Prognostic variables	B	SE	Wald value	P value	HR	Lower	Upper
Gender	0.051	0.205	0.063	0.802	1.053	0.705	1.572
Age (years)	0.262	0.130	4.037	0.045	1.299	1.006	1.677
Tumor size	0.031	0.187	0.027	0.869	1.031	0.715	1.487
Histological grade	0.541	0.179	9.184	0.002	1.718	1.211	2.438
Depth of invasion	0.235	0.204	1.325	0.250	1.264	0.848	1.885
Lymph node metastasis	−0.043	0.198	0.048	0.824	0.957	0.649	1.412
Distant metastasis	1.383	0.536	6.661	0.010	3.989	1.395	11.405
TNM stage	0.638	0.237	7.285	0.007	1.894	1.191	3.010
Lgr5 expression	1.018	0.274	13.842	0.001	2.768	1.619	4.732
Ki-67 expression	0.819	0.244	11.263	0.001	2.267	1.406	3.657

B, Partial regression coefficient; CI, Confidence interval; HR, Hazard ratio; SE, Standard error.
P<0.05, statistically significant.

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