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Table 1 Relationship of Lgr5 and Ki-67 expression to clinicopathological variables in colorectal cancer

From: Lgr5 is a potential marker of colorectal carcinoma stem cells that correlates with patient survival

Variables Lgr5 P value Ki-67 P value
+ - + -
Gender       
Male 66 54 P=0.652 71 49 P=0.940
Female 42 30   43 29  
Age (years)       
<45 18 11 P=0.791 19 10 P=0.707
45-60 32 26   35 23  
≥60 58 47   60 45  
Tumor size (cm)       
d<5 67 61 P=0.282 66 62 P=0.006
5≤d<10 37 20   42 15  
d≥10 4 3   6 1  
Histological grade       
1 6 16 P=0.001 10 12 P=0.001
2 52 55   54 53  
3 50 13   50 13  
Depth of invasion       
T1 1 6 P=0.001 2 5 P=0.001
T2 19 48   24 43  
T3 76 29   77 28  
T4 12 1   11 2  
Lymph node       
N0 50 73 P=0.001 58 65 P=0.001
N1 43 8   40 11  
N2 15 3   16 2  
Distant metastasis       
Negative 98 84 P=0.004 104 78 P=0.007
Positive 10 0   10 0  
TNM stage       
I 5 42 P=0.001 9 38 P=0.001
II 39 31   44 26  
III 54 11   51 14  
IV 10 0   10 0  
  1. P<0.05, statistically significant.