Lgr5 is a potential marker of colorectal carcinoma stem cells that correlates with patient survival

Table 1 Relationship of Lgr5 and Ki-67 expression to clinicopathological variables in colorectal cancer

Variables	Lgr5		P value	Ki-67		P value
Variables	+	-	P value	+	-	P value
Gender
Male	66	54	P=0.652	71	49	P=0.940
Female	42	30		43	29
Age (years)
<45	18	11	P=0.791	19	10	P=0.707
45-60	32	26		35	23
≥60	58	47		60	45
Tumor size (cm)
d<5	67	61	P=0.282	66	62	P=0.006
5≤d<10	37	20		42	15
d≥10	4	3		6	1
Histological grade
1	6	16	P=0.001	10	12	P=0.001
2	52	55		54	53
3	50	13		50	13
Depth of invasion
T1	1	6	P=0.001	2	5	P=0.001
T2	19	48		24	43
T3	76	29		77	28
T4	12	1		11	2
Lymph node
N0	50	73	P=0.001	58	65	P=0.001
N1	43	8		40	11
N2	15	3		16	2
Distant metastasis
Negative	98	84	P=0.004	104	78	P=0.007
Positive	10	0		10	0
TNM stage
I	5	42	P=0.001	9	38	P=0.001
II	39	31		44	26
III	54	11		51	14
IV	10	0		10	0

ISSN: 1477-7819