Figure 4From: Activity of pemetrexed and high-dose gefitinib in an EGFR-mutated lung adenocarcinoma with brain and leptomeningeal metastasis after response to gefitinib Mutational analysis of K-ras gene by pyrosequencing: a point mutation (arrow) in codon 12 (GGT→GAT; G12D) was detected. Back to article page