Figure 3From: Activity of pemetrexed and high-dose gefitinib in an EGFR-mutated lung adenocarcinoma with brain and leptomeningeal metastasis after response to gefitinibMutational analysis of EGFR gene by direct sequencing. A deletion of 15 nucleotides in exon 19 of the EGFR gene (2240-2254del15; L747-S752del5) is indicated by a blue arrow. A point mutation in exon 19 of the EGFR gene (A2262T; K754I) is indicated by a red arrow.Back to article page