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Table 1 Suggested guidelines for assessing the malignant potential of gastric GISTs of different sizes and mitotic activity

From: Long term survival results for gastric GIST: is laparoscopic surgery for large gastric GIST feasible?

Benign

 

Group 1 (no larger than 2 cm, no more than 5 mitoses/50 HPF)

Probably benign (very low malignant potential)

 

Group 2 (> 2 cm and ≤ 5 cm, no more than 5 mitoses/50 HPF)

Group 3a (> 5cm and ≤ 10 cm, no more than 5 mitoses/50 HPF)

Uncertain or low malignant potential

 

Group 4 (no larger than 2 cm, > 5 mitoses/50 HPF)

Low to moderate malignant potential

 

Group 3b (> 10 cm, no more than 5 mitoses/50 HPF)

 

Group 5 (> 2 cm and ≤ 5 cm, > 5 mitoses/50 HPF)

High malignant potential

 

Group 6a (> 5cm and ≤ 10 cm, > 5 mitoses/50 HPF)

 

Group 6b (> 10 cm, > 5 mitoses/50 HPF)

  1. From[7].
  2. GIST gastrointestinal stromal tumor, HPF high power field.