Table 1 Characteristics of patients and tumors according to CXCR4, CXCR7 and SDF-1 expression

Gender

 Male

60 (61.9)

22

38

17

43

41

19

 Female

37 (38.1)

15

22

0.703

8

29

0.463

29

8

0.284

Age (years)

 ≤60

62 (63.9)

23

39

18

44

44

18

 >60

35 (36.1)

14

21

0.777

7

28

0.329

26

9

0.726

Tumor size (cm)

 ≤4

20 ( 20.6 )

7

13

7

13

12

8

 4-7

50 (51.5)

20

30

14

36

37

13

 >7

27(27.9)

10

17

0.918

4

23

0.257

21

6

0.371

Symptoms at diagnosis

 Incidental

56 (57.7)

17

39

15

41

43

13

 Symptoms

41 (42.3)

20

21

0.065

10

31

0.79

27

14

0.235

AJCC stage

 T1

66 (68.0)

25

41

18

48

44

22

 T2

18 (18.6)

5

13

5

13

15

3

 T3 and T4

13 (13.4)

7

6

0.369

2

11

0.774

11

2

0.289

Lymph nodal status

 N0

20 (20.6)

11

9

6

14

15

5

 N1

5 (5.2)

1

4

1

4

2

3

 N_X

72 (74.2)

25

47

0.22

19

53

0.914

53

19

0.264

Metastasis

 M0

91 (93.8)

35

56

22

69

66

25

 M1

6 (6.2)

2

4

1

3

3

0.176

4

2

0.669

Histologic variant

 Clear cell

81 (83.5)

33

48

21

60

60

21

 Others

16 (16.5)

4

12

0.236

4

12

1

10

6

0.369

Fuhrman’s grade

 1

17 (17.5)

8

9

7

10

7

10

 2

50 (51.5)

19

31

13

37

41

9

 3

24 (24.7)

9

15

5

19

18

6

 4

6 (6.3)

1

5

0.676

0

6

0.235

4

2

0.015