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Table 1 Characteristics of patients and tumors according to CXCR4, CXCR7 and SDF-1 expression

From: High expression of CXCR4, CXCR7 and SDF-1 predicts poor survival in renal cell carcinoma

Characteristics N (%) CXCR4 P CXCR7 P SDF-1 P
Low High Low High Low High
Gender           
 Male 60 (61.9) 22 38   17 43   41 19  
 Female 37 (38.1) 15 22 0.703 8 29 0.463 29 8 0.284
Age (years)           
 ≤60 62 (63.9) 23 39   18 44   44 18  
 >60 35 (36.1) 14 21 0.777 7 28 0.329 26 9 0.726
Tumor size (cm)           
 ≤4 20 ( 20.6 ) 7 13   7 13   12 8  
 4-7 50 (51.5) 20 30   14 36   37 13  
 >7 27(27.9) 10 17 0.918 4 23 0.257 21 6 0.371
Symptoms at diagnosis           
 Incidental 56 (57.7) 17 39   15 41   43 13  
 Symptoms 41 (42.3) 20 21 0.065 10 31 0.79 27 14 0.235
AJCC stage           
 T1 66 (68.0) 25 41   18 48   44 22  
 T2 18 (18.6) 5 13   5 13   15 3  
 T3 and T4 13 (13.4) 7 6 0.369 2 11 0.774 11 2 0.289
Lymph nodal status           
 N0 20 (20.6) 11 9   6 14   15 5  
 N1 5 (5.2) 1 4   1 4   2 3  
 NX 72 (74.2) 25 47 0.22 19 53 0.914 53 19 0.264
Metastasis           
 M0 91 (93.8) 35 56   22 69   66 25  
 M1 6 (6.2) 2 4 1 3 3 0.176 4 2 0.669
Histologic variant           
 Clear cell 81 (83.5) 33 48   21 60   60 21  
 Others 16 (16.5) 4 12 0.236 4 12 1 10 6 0.369
Fuhrman’s grade           
 1 17 (17.5) 8 9   7 10   7 10  
 2 50 (51.5) 19 31   13 37   41 9  
 3 24 (24.7) 9 15   5 19   18 6  
 4 6 (6.3) 1 5 0.676 0 6 0.235 4 2 0.015