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Table 1 Summary of calcified VS cases

From: Calcification of vestibular schwannoma: a case report and literature review

Case

Author/year

Age/sex

Duration of disease

Symptoms and signs

Radiological findings

Surgical findings

Postoperative complications

1

[Thomsen/1984]

44/male

2 years

Progressive right-sided hearing loss with a unilateral sensorineural hearing impairment

CT: a mass with a size of 2 × 3 cm with a conglomerate of dense calcification in the right CPA, moderate enhancement after contrast injection, normal internal auditory canal

Approach: translabyrinthine craniotomy twice, subtotal removal of the tumor at the initial operation, and total removal of the tumor after 5 months

Dysdiadokinesis

Mild facial palsy

    

Examination: spontaneous nystagmus, gait disturbance, and a positive Romberg test

 

Tumor: whitish, hard, and highly vascularized

 

2

[Beskin/1989]

47/male

15 years

Progressive left-sided hearing loss with ringing and itching deep in the left canal

MRI: Hypointensity on T1WI and hyperintensity on T2WI

Approach: left posterior fossa craniotomy, total removal of the tumor after debulking

Mild facial palsy

    

Examination: no response in vestibular testing in the left labyrinth

CT: a 3 cm mass with pronounced calcification in the left CPA, enhancement after administration of contrast medium, enlarged internal auditory canal

Tumor: rubbery consistency

 

3

[Atlas/1992]

50/male

2 years

Progressive right-sided hearing loss with a unilateral sensorineural hearing impairment

CT: a small mass in the right enlarged internal auditory canal with a conglomerate of dense calcification

Approach: translabyrinthine craniotomy, total removal of the tumor with preservation of the facial nerve

Complete palsy

    

Examination: not described

 

Tumor: adhesion to the facial nerve

 

4

[Tosaka/2002]

36/male

30 years

Progressive left-sided hearing loss

MRI: a mass with a size of 3.5 × 3 × 2.5 cm in the CPA, hypointensity on T1WI and hyperintensity on T2WI, heterogeneous enhancement after gadolinium administration

Approach: left suboccipital craniotomy, removal of 90% of the tumor

Hearing was worse on the left side after surgery than before surgery

    

Examination: left hearing loss, left canal paresis

CT: significant calcification on the tumor that protruded to the enlarged internal auditory canal

Tumor: whitish, elastic, hard, fibrous, and demarcated with a rich blood supply

No facial palsy

     

DSA: no tumor stain

  

5

[Katoh/2007]

59/female

15 years

A long history of CPA tumor with no treatment, admitted to the hospital following an epileptic seizure

MRI: a mass with a 3 cm diameter in the CPA, heterogeneous intensity on T1WI and T2WI, heterogeneous enhancement after gadolinium administration

Approach: left suboccipital craniotomy, subtotal removal of the tumor

No facial palsy

    

Examination: left deafness, left nystagmus, and left cerebellar ataxia

CT: circular calcification in the periphery of the tumor

Tumor: yellow-grayish, soft, with rich blood supply and old hematoma inside the tumor

 
     

DSA: no tumor stain

  

6

[Gopalakrishnan/2011]

65/male

3 years

Progressive left-sided hearing loss with facial numbness

MRI: hypointensity on T1WI, and heterogeneous hyperintensity on T2WI, heterogeneous enhancement after gadolinium administration

Approach: left suboccipital craniotomy, total removal of the tumor

 
    

Examination: left hypoesthesia and facial palsy, and sensorineural hearing loss

CT: a mass with a 3 cm diameter in the left CPA with a conglomerate of dense calcification, and enlarged internal auditory canal

Tumor: not described

Death due to myocardial infarction

7

[Gopalakrishnan/2011]

31/female

6 months

Right-sided deafness with facial numbness

MRI: hypointensity on T1WI, and heterogeneous hyperintensity on T2WI, homogenous enhancement after gadolinium administration

Approach: left suboccipital craniotomy, total removal of the tumor

 
    

Examination: hypoesthesia on the right side of the face, and right sensorineural hearing loss

CT: a mass with a 5 cm diameter in the left CPA with two local deposits of calcification at the periphery of the tumor, and enlarged internal auditory canal

Tumor: not described

Facial palsy (with unknown severity)

8

Present case

48/male

3 years

Progressive left-sided hearing loss

MRI: a mass with a size of 5.42 × 4.27 × 5.35 cm in the left CPA, hypointensity on T1WI, hyperintensity on T2WI, and heterogeneous enhancement in the contrast-enhanced MRI

Approach: left suboccipital craniotomy, total removal of the tumor with preservation of the facial nerve

No improvement in left hearing

    

Examination: left hearing loss, left cerebellar ataxia

CTA: a high-density patchy calcification on the left CPA, no intracranial artery malformation, and no tumor stain

Tumor: yellow-grayish in color, soft and brittle in texture with a rich blood supply, and cysts found in the center of the tumor

Mild facial palsy