Figure 2

(a) Case 1. Histopathologic examination showed that the tumor cells had numerous granules, and immunostaining revealed S-100-positive (H&E staining, × 100). (b) Case 3. Histopathologic examination showed a submucosal tumor consisting of cells containing eosinophilic granules, and immunostaining revealed S-100-positive. The tumor was not a metastasis of esophageal cancer, and had no signs of malignancy (H&E staining, × 1). (c) Case 5. Histopathologic examination revealed a tumor in the striated muscular tissue. The tumor cells possessed numerous eosinophilic granules, and the tumor itself consisted of a dense proliferation of large tumor cells (H&E staining, × 200). d: Case 6. Histopathologic examination revealed eosinophilic granules inside the cell bodies. The cell nucleus was oval, and the nucleoplasmic ratio was low (H&E staining, × 400).