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Table 2 Univariate analysis predicting necrosis at PC-RPLND

From: Predicting necrosis in residual mass analysis after retroperitoneal lymph node dissection: a retrospective study

 

Necrosis

Teratoma orviable GCT

PValue

Components at orchiectomyhistology (%):

   

Embryonal

22.7 ± 30.1

32.9 ± 29.7

0.370

Yolk sac

4.3 ± 11.5

4.1 ± 8.0

0.737

Teratoma

12.7 ± 23.7

13.8 ± 17.1

0.502

Endodermal sinus

1.7 ± 4.5

5.0 ± 11.7

0.628

Retroperitonial node size

   

RP node cm before chemotherapy

6.5 ± 4.1

6.1 ± 5.5

0.849

RP node cm after chemotherapy

3.2 ± 1.8

5.3 ± 4.8

0.331

Relative change in RP node size

31.9 ± 48.3

9.4 ± 38.8

0.044

Absolute change in RP node size

3.2 ± 2.9

0.78 ± 2.9

0.053

Relative reduction in RP node

56.4 ± 14.0

26.2 ± 20.1

<0.001

Relative enlargement in RP node

35.6 ± 44.1

60.1 ± 22.5

0.425

Serum markers

   

hCG after chemotherapy

0.0

0.0

**

AFP after chemotherapy

1.3 ± 0.4

22.1 ± 49.3

<0.001

Relative change in AFP afterchemotherapy

15.7 ± 46.7

−83.7 ± 5.13

0.075

LDH after chemotherapy

307.7 ± 60.7

324.0 ± 65.8

0.399

Relative change in LDH afterchemotherapy

1.5 ± 15.9

0.68 ± 27.4

0.915

  1. ** unable to calculate. Data expressed as mean ± standard deviation. AFP, alpha-fetoprotein; GCT, germ cell tumor; hCG, human chorionic gonadotropin; LDH, lactate dehydrogenase; PC-RPLND, post-chemotherapy retroperitoneal lymph node dissection; RP, retroperitoneal.