24 h | Dose | HCA7 | HT29 | LoVo | |||
---|---|---|---|---|---|---|---|
aspirin | rofecoxib | aspirin | rofecoxib | aspirin | rofecoxib | ||
 | A | 2.0 ± 1.3 | 1.7 ± 1.4 | 1.2 ± 0.9 | 1.3 ± 0.9 | 1.0 ± 0.3 | 0.9 ± 0.5 |
 | B | 2.9 ± 1.9 | 1.6 ± 0.6 | 1.9 ± 1.3 | 1.1 ± 0.2 | 1.5 ± 0.6 | 1.7 ± 1.3 |
 | C | 2.4 ± 1.1 | 2.2 ± 0.8 | 1.7 ± 0.7 | 1.8 ± 0.8 | 1.5 ± 0.6 | 1.8 ± 1.0 |
48 h | Dose | HCA7 | HT29 | LoVo | |||
aspirin | rofecoxib | aspirin | rofecoxib | aspirin | rofecoxib | ||
A | 2.3 ± 1.2 | 2.3 ± 1.4 | 2.0 ± 0.9 | 1.5 ± 0.6 | 1.8 ± 0.6 | 1.4 ± 0.8 | |
B | 3.6 ± 1.8 | 2.5 ± 0.8 | 2.6 ± 1.7 | 2.2 ± 1.0 | 2.7 ± 1.2 | 2.4 ± 1.3 | |
C | 6.0 ± 2.7 | 3.8 ± 1.4 | 3.7 ± 1.7 | 2.4 ± 1.4 | 2.7 ± 1.2 | 2.7 ± 0.9 | |
72 h | Dose | HCA7 | HT29 | LoVo | |||
aspirin | rofecoxib | aspirin | rofecoxib | aspirin | rofecoxib | ||
A | 4.6 ± 1.7 | 2.9 ± 1.6 | 3.4 ± 1.6 | 3.0 ± 1.8 | 2.5 ± 1.0 | 2.4 ± 0.8 | |
B | 5.0 ± 1.6 | 3.5 ± 2.0 | 4.8 ± 2.3 | 2.9 ± 1.4 | 2.8 ± 0.9 | 2.3 ± 1.0 | |
C | 7.7 ± 1.9 | 4.0 ± 1.6 | 6.5 ± 2.0 | 4.1 ± 1.8 | 5.3 ± 1.8 | 2.9 ± 1.6 |