Figure 1
Effect of aspirin and rofecoxib on (A) prostaglandin E 2 and (B) leukotriene B4 secretion by different cell lines. Cells were cultured without agents (dose 0); with 1 μ M rofecoxib, 10 μ M aspirin (dose 1); 10 μ M rofecoxib, 100 μ M aspirin (dose 2); or 100 μ M rofecoxib, 1,000 μ M aspirin (dose 3). Mean and standard deviations of triplicate cultures shown. (**P <0.001) (** = P<0.001).