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Table 1 Clinical Features of 45 Cases of Primary Hepatic Malignant Fibrous Histiocytoma in the English literature

From: Clinical characteristics of the primary hepatic malignant fibrous histiocytoma in China: case report and review of the literature

References/Published date Authors No. Cases Age/Sex Presentation Location Size (Largest Dimension, cm) Therapy Follow-up/Outcome
5 1985 Alberti-Flor et al 1 59/M Abdominal pain, anorexia, low fever, weight loss Right and left lobe 18 Surgery 2 w/died of tumor
6 1985 Conran et al 1 61/M Abdominal pain, anorexia, jaundice, weight loss Right and left 7 Puncture biopsy 18 d/died of tumor
7 1986 Fukayama et al 1 38/F Hepatic mass Left lobe 7 Surgery 4 y/alive without recurrence
8 1987 Arends et al 1 78/F Abdominal discomfort, anorexia,shortness of breath; Right and left lobe > 10 Palliative 6 d/died of tumor
9 1988 Bruneton et al 2 52/F Abdominal pain Right lobe 10 Surgery 2 y/alive without recurrence
     34/M Abdominal pain Right lobe 13 Palliative operation 6 mo/died of tumor
10 1988 Honda et al 1 71/F Weight loss, fatigue, fever Right lobe > 10 Puncture biopsy, chemoembolization 4 mo/died of tumor
11 1988 Katsuda et al 1 61/M Abdominal discomfort Right lobe 8.5 Surgery and chemotherapy 6 mo/died of tumor
12 1991 Hamasaki et al 1 35/M Abdominal fullness, palpable mass Left lobe 9.1 Surgery, Intraarterial therapy, later liver transplant 34 mo/died of lung metastasis
13 1992 Akifuji et al 1 79/M Anorexia, fatigue Left lobe 8 Chemoembolization, Surgery 5 mo/recurrence
14 1992 Zornig et al 1 36/F Abdominal pain N/A 7 Surgery, postoperate chemotherapy 63 mo/alive without tumor
15 1992 McGrady et al 1 53/F Left-sided chest pain Left lobe 14 (operation) Surgery, 5 years later recured, surgery again 9 y/alive without tumor after second surgery
16 1993 Reed et al 1 52/M Spike fever Right lobe > 10 Surgery, postoperate chemotherapy 2 mo/died of metastasis
17 1994 Pinson et al 1 41/M Abdominal pain, weight loss Right and left 11.5 Surgery 10 and a half mo/died of recurrence and metastasis
18 1998 Fujita et al 1 70/M Malaise, anorexia, fever, weight loss Right and left 12 Puncture biopsy, Surgery 3 mo/died of tumor
19 1998 Wunderbaldinger et al 1 56/F Palpable mass, lower extremity swelling Right lobe > 10 Surgery N/A
20 1998 Ferrozzi et al 3 62/F Abdominal pain, malaise, low-grade fever, and weight loss Right lobe > 12 Surgery 3 y/alive without recurrence
     67/F Abdominal pain, weight loss, malaise and palpable mass. Right and left > 12 Biopsy, palliative chemotherapy. N/A
     69/M Abdominal pain, weight loss, fatigue and anorexia. Right and left > 12 Puncture biopsy, palliative chemotherapy N/A
21 1999 Yu et al 5 40-69(53)/4M, 1F Abdominal discomfort*4, right shoulder and chest pain*1 Right lobe *3, left lobe *2 7-19 (mean 13) Surgery*5 N/A*5
22 1999 Maekawa et al 1 68/M Malaise Right lobe 6 Surgery N/A
23 2005 Anagnostopoulos et al 1 87/F Abdominal pain, weight loss, low fever Right lobe 12(CT) Puncture biopsy 6 mo/died of tumor
24 2006 Ding et al 1 50/M Abdominal pain, fatigue, weight loss Right and left 14.2(CT) Biopsy after laparotomy 2 mo/died of tumor
25 2007 Ye et al 1 50/M Abdominal pain, weight loss Left lobe 16 Surgery 4 mo/died of recurrence and metastasis
26 2007 Chen et al 1 70/M Abdominal pain, weight loss Right lobe 12.4(CT) Palliative operation 1 mo/died of tumor
27 2008 Li et al 7 77/F Spiking fever, weight loss Right lobe 10 Lobectomy 1 y/died of tumor
     54/M Abdominal pain, weight loss Left lobe 5.5 Lobectomy 4 y/died of tumor
     34/F Abdominal pain Right lobe 14 Liver and lung Lobectomy 4 mo/died of tumor
     80/F Abdominal discomfort, weight loss Right lobe 20 Palliative 1 y/died of tumor
     68/F Abdominal pain Right and left 2 N/A N/A
     46/F Abdominal pain Right lobe 12 Gleevecineffective 3 mo/alive, tumor larger but no metastasis
     70/M Incidental finding Right lobe 11 Lobectomy 4 y/no recurrence
28 2009 Sugitani et al 2 45/F Abdominal pain Left lobe 11 Surgery, 2 years and 5 months later recured, surgery again 34 mo/died of tumor metastasis
     70/F Jaundice Right lobe 12 Preoperate chemotherapy, Surgery 8 mo/died of tumor metastasis
29 2009 Kim et al 1 60/M Abdominal pain, weight loss Right lobe 14 Surgery 41 mo/alive without recurrence
30 2010 Caldeira et al 1 63/M Abdominal discomfort, lower extremities edema and weight loss. Right lobe N/A Puncture biopsy 45 d/died of tumor
31 2011 Cong et al 5 50-71(59)/2M, 3F Abdominal pain or discomfort*4, weight loss*1 Right lobe *2, left lobe *1, right and left*1, N/A*1 2.5-16 Surgery*5 N/A*5
  1. † indicates containing cases that were diagnosed as myxoid MFH; ‡ giant cell-type MFH